← Mechanisms of action

Glutamate NMDA receptor; GRIN1/GRIN2A

PROTEIN COMPLEXHomo sapiens

Linked proteins

Drugs acting on this target (5)

Active Pharmaceutical Ingredient Mechanism Type Approval Status API Type Mechanism of Action
cyclopropaneAntagonistmarketedSmall moleculeGlutamate NMDA receptor; GRIN1/GRIN2A antagonist
ketobemidone (Ketogan)AntagonistexperimentalSmall moleculeGlutamate NMDA receptor; GRIN1/GRIN2A antagonist
bupivacaine (Exparel)InhibitorexperimentalSmall moleculeGlutamate NMDA receptor; GRIN1/GRIN2A inhibitor
ifenprodilInhibitorexperimentalSmall moleculeGlutamate NMDA receptor; GRIN1/GRIN2A inhibitor
sage-718InhibitorexperimentalSmall moleculeGlutamate NMDA receptor; GRIN1/GRIN2A inhibitor