CDEK
← Mechanisms of action

Topoisomerase I

SINGLE PROTEINBos taurus

Linked proteins

Drugs acting on this target (22)

Active Pharmaceutical Ingredient Mechanism Type ▲ Approval Status API Type Mechanism of Action
peel-224AntagonistexperimentalSmall moleculetopoisomerase I
7-t-butyldimethylsilyl-10-hydroxycamptothecinInhibitorexperimentalSmall moleculeTopoisomerase I inhibitor
abi-011InhibitorexperimentalSmall moleculeTopoisomerase I inhibitor
bn80927InhibitorexperimentalSmall moleculeTopoisomerase I inhibitor
camptothecinInhibitorexperimentalSmall moleculeTopoisomerase I inhibitor
camptothecin-20-o-propionate hydrateInhibitorexperimentalSmall moleculeTopoisomerase I inhibitor
daniquidoneInhibitorexperimentalSmall moleculeTopoisomerase I inhibitor
diflomotecanInhibitorexperimentalSmall moleculeTopoisomerase I inhibitor
gsk945237InhibitorexperimentalSmall moleculeTopoisomerase I inhibitor
intoplicineInhibitorexperimentalSmall moleculeTopoisomerase I inhibitor
lipotecanInhibitorexperimentalSmall moleculeTopoisomerase I inhibitor
lmp 400InhibitorexperimentalSmall moleculeTopoisomerase I inhibitor
lmp 776InhibitorexperimentalSmall moleculeTopoisomerase I inhibitor
lurtotecanInhibitorexperimentalSmall moleculeTopoisomerase I inhibitor
pegamotecanInhibitorexperimentalSmall moleculeTopoisomerase I inhibitor
samrotecanInhibitorexperimentalSmall moleculeTopoisomerase I inhibitor
simmitecanInhibitorexperimentalSmall moleculeTopoisomerase I inhibitor
sinotecanInhibitorexperimentalSmall moleculeTopoisomerase I inhibitor
sn-38InhibitorexperimentalSmall moleculeTopoisomerase I inhibitor
st1481InhibitorexperimentalSmall moleculeTopoisomerase I inhibitor
tq-b3203InhibitorexperimentalSmall moleculeTopoisomerase I inhibitor
tqb3702InhibitorexperimentalSmall moleculeTopoisomerase I inhibitor