CDEK
← Mechanisms of action

CD4

SINGLE PROTEINHomo sapiens
Preferred name: T-cell surface antigen CD4 ChEMBL ↗

Linked proteins

Drugs acting on this target (31)

Active Pharmaceutical Ingredient Mechanism Type ▲ Approval Status API Type Mechanism of Action
tregalizumabAgonistexperimentalmAbCD4 agonist
10e8.4/imabAntagonistexperimentalmAbCD4 antagonist
13B8.2AntagonistexperimentalmAbCD4
B-F5AntagonistexperimentalmAbCD4
cM-T412AntagonistexperimentalmAbCD4
IDEC-CE9AntagonistexperimentalmAbCD4
tmb-380AntagonistexperimentalmAbCD4
vrc-hivmab080-00-abBinding agentexperimentalmAbT-cell surface antigen CD4 binding agent
cd4 car-t cellImmunity, passiveexperimentalCell therapyCD4 immunity, passive
cd4 car+ccr5 zfn t-cellsImmunity, passiveexperimentalCell therapyCD4 immunity, passive
cd4⁺ car⁺ foxp3⁺ cellsImmunity, passiveexperimentalCell therapyCD4 immunity, passive
lb1901Immunity, passiveexperimentalCell therapyCD4 immunity, passive
lcar-t2c car-t cellsImmunity, passiveexperimentalCell therapyCD4 immunity, passive
alvircept sudotoxInhibitorexperimentalRecombinant proteinCD4 inhibitor
cedelizumabInhibitorexperimentalmAbCD4 inhibitor
clenoliximabInhibitorexperimentalmAbCD4 inhibitor
ep 1645InhibitorexperimentalmAbCD4 inhibitor
fab-fragment of anti-human cd4InhibitorexperimentalmAbCD4 inhibitor
ibalizumab-uiyk (trogarzo)InhibitorapprovedmAbCD4 inhibitor
keliximabInhibitorexperimentalmAbCD4 inhibitor
m-t412InhibitorexperimentalmAbCD4 inhibitor
priliximabInhibitorexperimentalmAbCD4 inhibitor
tregalizumabInhibitorexperimentalmAbCD4 inhibitor
trx-1InhibitorexperimentalmAbCD4 inhibitor
ub-421InhibitorexperimentalmAbCD4 inhibitor
vrc-hivmab060-00-abInhibitorexperimentalmAbCD4 inhibitor
vrc-hivmab091-00-abInhibitorexperimentalmAbCD4 inhibitor
vrc07-523lsInhibitorexperimentalmAbCD4 inhibitor
keliximabNegative modulatorexperimentalmAbCD4 negative modulator
priliximabNegative modulatorexperimentalmAbCD4 negative modulator
zanolimumabOtherexperimentalmAbCD4 other