CDEK
← Mechanisms of action

BCL2

SINGLE PROTEINHomo sapiens
Preferred name: Apoptosis regulator Bcl-2 ChEMBL ↗

Linked proteins

Drugs acting on this target (29)

Active Pharmaceutical Ingredient Mechanism Type ▲ Approval Status API Type Mechanism of Action
bp1002Antisense inhibitorexperimentalNucleic acidBCL2
peptides derived from anti-apoptotic proteins from the bcl-2 family,Immunity, activeexperimentalVaccineBCL2 immunity, active
abbv-453InhibitorexperimentalSmall moleculeBCL2 inhibitor
abbv-623InhibitorexperimentalSmall moleculeBCL2 inhibitor
apg-1252InhibitorexperimentalSmall moleculeBCL2 inhibitor
as1411InhibitorexperimentalNucleic acidBCL2 inhibitor
bcl-2 antisense oligonucleotideInhibitorexperimentalNucleic acidBCL2 inhibitor
bcl201InhibitorexperimentalSmall moleculeBCL2 inhibitor
bgb-11417InhibitorexperimentalSmall moleculeBCL2 inhibitor
bgb-21447InhibitorexperimentalSmall moleculeBCL2 inhibitor
fcn-338InhibitorexperimentalSmall moleculeBCL2 inhibitor
icp-248InhibitorexperimentalSmall moleculeBCL2 inhibitor
LisaftoclaxInhibitorexperimentalSmall moleculeBCL2 inhibitor
loxo-338InhibitorexperimentalSmall moleculeBCL2 inhibitor
lp-108InhibitorexperimentalSmall moleculeBCL2 inhibitor
lp-118InhibitorexperimentalSmall moleculeBCL2 inhibitor
mik665InhibitorexperimentalSmall moleculeBCL2 inhibitor
navitoclaxInhibitorexperimentalSmall moleculeBCL2 inhibitor
obatoclaxInhibitorexperimentalSmall moleculeBCL2 inhibitor
oblimersen sodiumInhibitorexperimentalNucleic acidBCL2 inhibitor
pnt2258InhibitorexperimentalNucleic acidBCL2 inhibitor
s 55746InhibitorexperimentalSmall moleculeBCL2 inhibitor
s65487InhibitorexperimentalSmall moleculeBCL2 inhibitor
spc2996InhibitorexperimentalSmall moleculeBCL2 inhibitor
tgrx-814InhibitorexperimentalSmall moleculeBCL2 inhibitor
tqb3909InhibitorexperimentalSmall moleculeBCL2 inhibitor
venetoclax (venclexta)InhibitorapprovedSmall moleculeBCL2 inhibitor
ze 50-0134InhibitorexperimentalSmall moleculeBCL2 inhibitor
zn-d5InhibitorexperimentalSmall moleculeBCL2 inhibitor