← Mechanisms of action
FOLR1
SINGLE PROTEINHomo sapiens
Preferred name: Folate receptor alpha ChEMBL ↗
Linked proteins
Drugs acting on this target (41)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| amt-151 | Agonist | experimental | mAb | FOLR1 agonist |
| folic acid | Agonist | approved | Small molecule | FOLR1 agonist |
| bat8006 | Antagonist | experimental | mAb | Folate receptor alpha |
| 99mtc ec20 | Binding agent | experimental | Small molecule | FOLR1 binding agent |
| azd5335 | Binding agent | experimental | mAb | FOLR1 binding agent |
| ec0489 | Binding agent | experimental | Small molecule | FOLR1 binding agent |
| ec1456 | Binding agent | experimental | Small molecule | FOLR1 binding agent |
| elu001 | Binding agent | experimental | mAb | FOLR1 binding agent |
| epofolate | Binding agent | experimental | Small molecule | FOLR1 binding agent |
| etarfolatide | Binding agent | experimental | Small molecule | FOLR1 binding agent |
| imgn151 | Binding agent | experimental | mAb | FOLR1 binding agent |
| mirvetuximab soravtansine (Elahere) | Binding agent | approved | mAb | FOLR1 binding agent |
| oc-tr | Binding agent | experimental | mAb | FOLR1 binding agent |
| pro1184 | Binding agent | experimental | mAb | FOLR1 |
| vynfinit | Binding agent | experimental | Small molecule | FOLR1 binding agent |
| e39 vaccine | Immunity, active | experimental | Vaccine | FOLR1 immunity, active |
| fbp peptide | Immunity, active | experimental | Vaccine | FOLR1 immunity, active |
| fralpha peptide | Immunity, active | experimental | Vaccine | FOLR1 immunity, active |
| fralpha vaccine | Immunity, active | experimental | Vaccine | FOLR1 immunity, active |
| j65 vaccine | Immunity, active | experimental | Vaccine | FOLR1 immunity, active |
| multi-epitope folate receptor alpha peptide vaccine | Immunity, active | experimental | Vaccine | FOLR1 immunity, active |
| tpiv200 | Immunity, active | experimental | Vaccine | FOLR1 immunity, active |
| 4scar-fra | Immunity, passive | experimental | Cell therapy | FOLR1 immunity, passive |
| folr1 car t-cells | Immunity, passive | experimental | Cell therapy | FOLR1 immunity, passive |
| mov-gamma chimeric receptor gene | Immunity, passive | experimental | Cell therapy | FOLR1 immunity, passive |
| cbp-1008 | Inhibitor | experimental | Recombinant protein | FOLR1 inhibitor |
| cbp-1018 | Inhibitor | experimental | mAb | FOLR1 inhibitor |
| ch-1504 | Inhibitor | experimental | Small molecule | FOLR1 inhibitor |
| ch-4051 | Inhibitor | experimental | Small molecule | FOLR1 inhibitor |
| farletuzumab | Inhibitor | experimental | mAb | FOLR1 inhibitor |
| gensci140 | Inhibitor | experimental | mAb | FOLR1 inhibitor |
| ly4170156 | Inhibitor | experimental | mAb | FOLR1 inhibitor |
| mirvetuximab soravtansine (Elahere) | Inhibitor | approved | mAb | FOLR1 inhibitor |
| morab-202 | Inhibitor | experimental | mAb | FOLR1 inhibitor |
| sibp-a19 | Inhibitor | experimental | mAb | FOLR1 inhibitor |
| stro-002 | Inhibitor | experimental | mAb | FOLR1 inhibitor |
| talotrexin | Inhibitor | experimental | Small molecule | FOLR1 inhibitor |
| ub_tt170 | Inhibitor | experimental | Small molecule | FOLR1 inhibitor |
| Vintafolide | Inhibitor | experimental | Small molecule | FOLR1 inhibitor |
| zw191 | Inhibitor | experimental | mAb | FOLR1 inhibitor |
| ga-ec2115 | Radiopharmaceutical | experimental | Small molecule | FOLR1 radiopharmaceutical |