ch-1504
Small moleculeexperimental
Clinical trial activity
1 trials · 2 clinical orgs · 0 marketing orgs
Phase 1
0
Phase 2
1
Phase 3
0
Phase 4
0
Earliest trial started Apr 1, 2008 (NCT00658047)
Timeline
2000s
- Jan 1, 2008
Earliest Phase 2 Sponsor(trial)
Indications
Studied for
Mechanism of action
- Folate receptor alphaINHIBITOR
FOLR1 inhibitor
Chemistry & pharmacology
Loading structure…
SMILES
C=C(CC(NC(=O)c1ccc(CCc2ccc3nc(N)nc(N)c3c2)cc1)C(=O)O)C(=O)O- Mol. weight
- 449.47 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Achiral Molecule
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL4802141 ↗
Also known as
- 4'-methylene-5,8,10-trideazaaminopterin
- ch-1504
- ch-1504
- ch-1504
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT00658047 | Phase 2 | Apr 1, 2008 | Chelsea Therapeutics, University of Toronto |
Showing 1 of 1 trials
Page 1 / 1
Organizations
Research & Development (2)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Chelsea Therapeutics | For profit | 1 | 1 | 1 | 2008 |
| University of Toronto | Academic/Hospital | 1 | 0 | 1 | 2008 |
2 organizations
Page 1 / 1