← Mechanisms of action
HCRTR1
SINGLE PROTEINHomo sapiens
Preferred name: Orexin receptor 1 ChEMBL ↗
Linked proteins
Drugs acting on this target (7)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| azd4041 | Agonist | experimental | Small molecule | HCRTR1 agonist |
| act-539313 | Antagonist | experimental | Small molecule | HCRTR1 antagonist |
| daridorexant (Quviviq) | Antagonist | approved | Small molecule | Orexin receptor 1 antagonist |
| gsk649868 | Antagonist | experimental | Small molecule | HCRTR1 antagonist |
| jnj-61393215 | Antagonist | experimental | Small molecule | HCRTR1 antagonist |
| lemborexant (Dayvigo) | Antagonist | approved | Small molecule | HCRTR1 antagonist |
| cvn766 | Inhibitor | experimental | Small molecule | HCRTR1 inhibitor |