← Mechanisms of action
ELANE
SINGLE PROTEINHomo sapiens
Preferred name: Leukocyte elastase ChEMBL ↗
Linked proteins
Drugs acting on this target (12)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| alpha-1 antitrypsin (Prolastin) | Inhibitor | approved | Biological | Leukocyte elastase inhibitor |
| alvelestat | Inhibitor | experimental | Small molecule | ELANE inhibitor |
| azd6553 | Inhibitor | experimental | Small molecule | ELANE inhibitor |
| azd9668 | Inhibitor | experimental | Small molecule | ELANE inhibitor |
| azd9819 | Inhibitor | experimental | Small molecule | ELANE inhibitor |
| bay85-8501 | Inhibitor | experimental | Small molecule | ELANE inhibitor |
| chf6333 | Inhibitor | experimental | Small molecule | ELANE inhibitor |
| depelestat | Inhibitor | experimental | Recombinant protein | ELANE inhibitor |
| php-303 | Inhibitor | experimental | Small molecule | ELANE inhibitor |
| pk101 | Inhibitor | experimental | Small molecule | ELANE inhibitor |
| pol6014 | Inhibitor | experimental | Small molecule | ELANE inhibitor |
| sivelestat | Inhibitor | experimental | Small molecule | Leukocyte elastase inhibitor |