azd9668
Small moleculeexperimental
Clinical trial activity
13 trials · 15 clinical orgs · 0 marketing orgs
Phase 1
6
Phase 2
8
Phase 3
0
Phase 4
0
Earliest trial started Jun 1, 2008 (NCT00703391)
Timeline
Indications
Mechanism of action
- Leukocyte elastaseINHIBITOR
ELANE inhibitor
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Also known as
- azd9668
- azd9668
- azd9668
- n-((5-(methanesulfonyl)pyridin-2-yl)methyl)-6-methyl-5-(1-methyl-1h-pyrazol-5-yl)-2-oxo-1-(3-(trifluoromethyl)phenyl)-1,2-dihydropyridine-3-carboxamide
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT02669251 | Phase 1/Phase 2 (Phase 2) | Jan 20, 2016 | National Cancer Institute (NCI) |
| NCT02597101 | Phase 2 | Nov 1, 2015 | Allegheny Health Network, Allegheny Singer Research Institute, AstraZeneca, National Institutes of Health (NIH), University of Pittsburgh, University of South Florida |
| NCT01214122 | Phase 1 | Nov 1, 2010 | AstraZeneca, Berzelius Clinical Research Center, IQVIA |
| NCT01161355 | Phase 1 | Jun 1, 2010 | AstraZeneca, IQVIA |
| NCT01147549 | Phase 1 | Jun 1, 2010 | AstraZeneca, IQVIA |
| NCT01054170 | Phase 2 | Jan 1, 2010 | AstraZeneca, University of Copenhagen |
| NCT01035411 | Phase 1 | Nov 1, 2009 | AstraZeneca, Parexel |
| NCT01023516 | Phase 2 | Nov 1, 2009 | AstraZeneca, Samodzielny Publiczny Szpital |
| NCT01034982 | Phase 1 | Nov 1, 2009 | AstraZeneca, Parexel |
| NCT00949975 | Phase 2 | Jul 1, 2009 | AstraZeneca, Philipps University of Marburg |
| NCT00757848 | Phase 2 | Oct 1, 2008 | AstraZeneca, Queen's University, Belfast |
| NCT00769119 | Phase 2 | Sep 1, 2008 | AstraZeneca, Queen Elizabeth Hospital NHS Foundation Trust |
| NCT00703391 | Phase 2 | Jun 1, 2008 | AstraZeneca, Parexel |
Showing 13 of 13 trials
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Organizations
Research & Development (15)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| AstraZeneca | For profit | 12 | 11 | 2 | 2008 |
| IQVIA | For profit | 3 | 0 | 1 | 2010 |
| Parexel | For profit | 3 | 0 | 2 | 2008 |
| Allegheny Health Network | Academic/Hospital | 1 | 0 | 1 | 2015 |
| Allegheny Singer Research Institute | Academic/Hospital | 1 | 1 | 1 | 2015 |
| Berzelius Clinical Research Center | Academic/Hospital | 1 | 0 | 1 | 2010 |
| National Cancer Institute (NCI) | Government | 1 | 1 | 1 | 2016 |
| National Institutes of Health (NIH) | Government | 1 | 0 | 1 | 2015 |
| Philipps University of Marburg | Academic/Hospital | 1 | 0 | 1 | 2009 |
| Queen Elizabeth Hospital NHS Foundation Trust | Academic/Hospital | 1 | 0 | 1 | 2008 |
| Queen's University, Belfast | Academic/Hospital | 1 | 0 | 1 | 2008 |
| Samodzielny Publiczny Szpital | Academic/Hospital | 1 | 0 | 1 | 2009 |
| University of Copenhagen | Academic/Hospital | 1 | 0 | 1 | 2010 |
| University of Pittsburgh | Academic/Hospital | 1 | 0 | 1 | 2015 |
| University of South Florida | Academic/Hospital | 1 | 0 | 1 | 2015 |
15 organizations
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