← Mechanisms of action
HCRTR2
SINGLE PROTEINHomo sapiens
Preferred name: Orexin receptor 2 ChEMBL ↗
Linked proteins
Drugs acting on this target (11)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| alks 2680 | Agonist | experimental | Small molecule | HCRTR2 agonist |
| orx142 | Agonist | experimental | Small molecule | HCRTR2 agonist |
| tak-360 | Agonist | experimental | Small molecule | HCRTR2 agonist |
| tak-861 | Agonist | experimental | Small molecule | HCRTR2 agonist |
| tak-988 | Agonist | experimental | Small molecule | HCRTR2 agonist |
| daridorexant (Quviviq) | Antagonist | approved | Small molecule | Orexin receptor 2 antagonist |
| gsk649868 | Antagonist | experimental | Small molecule | HCRTR2 antagonist |
| jnj-48816274 | Antagonist | experimental | Small molecule | HCRTR2 antagonist |
| lemborexant (Dayvigo) | Antagonist | approved | Small molecule | HCRTR2 antagonist |
| mk-1064 | Antagonist | experimental | Small molecule | HCRTR2 antagonist |
| seltorexant | Antagonist | experimental | Small molecule | Orexin receptor 2 antagonist |