← Mechanisms of action
ITGAV
SINGLE PROTEINHomo sapiens
Preferred name: Vitronectin receptor alpha ChEMBL ↗
Linked proteins
Drugs acting on this target (20)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| cend-1 | Antagonist | experimental | Peptide | ITGAV antagonist |
| cilengitide | Antagonist | experimental | Peptide | ITGAV antagonist |
| tc99m maraciclatide | Antagonist | experimental | Peptide | ITGAV antagonist |
| alfatide | Binding agent | experimental | Small molecule | ITGAV binding agent |
| fba-a20fmdv2 | Binding agent | experimental | Peptide | ITGAV binding agent |
| imgn-388 | Binding agent | experimental | mAb | ITGAV binding agent |
| 99mtc-3prgd2 | Inhibitor | experimental | Small molecule | ITGAV inhibitor |
| abituzumab | Inhibitor | experimental | mAb | ITGAV inhibitor |
| etaracizumab (abegrin) | Inhibitor | experimental | mAb | ITGAV inhibitor |
| imgn-388 | Inhibitor | experimental | mAb | ITGAV inhibitor |
| intetumumab | Inhibitor | experimental | mAb | ITGAV inhibitor |
| mk0429 | Inhibitor | experimental | Small molecule | ITGAV inhibitor |
| np-011 | Inhibitor | experimental | Recombinant protein | ITGAV inhibitor |
| ott166 | Inhibitor | experimental | Small molecule | ITGAV inhibitor |
| pln-101095 | Inhibitor | experimental | Small molecule | ITGAV inhibitor |
| rgd peptide | Inhibitor | experimental | Peptide | ITGAV inhibitor |
| sf0166 | Inhibitor | experimental | Small molecule | ITGAV inhibitor |
| thr-687 | Inhibitor | experimental | Small molecule | ITGAV inhibitor |
| vip236 | Inhibitor | experimental | Small molecule | ITGAV inhibitor |
| 68ga-tate-rgd | Radiopharmaceutical | experimental | Peptide | ITGAV radiopharmaceutical |