← Mechanisms of action
PPARA
SINGLE PROTEINHomo sapiens
Preferred name: Peroxisome proliferator-activated receptor alpha ChEMBL ↗
Linked proteins
Drugs acting on this target (26)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| cj-30039 | Activator | experimental | Small molecule | PPARA activator |
| lanifibranor | Activator | experimental | Small molecule | PPARA activator |
| aleglitazar | Agonist | experimental | Small molecule | PPARA agonist |
| ave8134 | Agonist | experimental | Small molecule | PPARA agonist |
| ciprofibrate | Agonist | experimental | Small molecule | PPARA agonist |
| clofibrate (atromid-s) | Agonist | approved | Small molecule | PPARA agonist |
| cp-778875 | Agonist | experimental | Small molecule | PPARA agonist |
| drf-10945 | Agonist | experimental | Small molecule | PPARA agonist |
| elafibranor (IQIRVO) | Agonist | approved | Small molecule | Peroxisome proliferator-activated receptor alpha agonist |
| fenofibrate (fenoglide) | Agonist | approved | Small molecule | PPARA agonist |
| gemfibrozil (lopid) | Agonist | approved | Small molecule | PPARA agonist |
| gw590735 | Agonist | experimental | Small molecule | PPARA agonist |
| imiglitazar | Agonist | experimental | Small molecule | PPARA agonist |
| k-877 | Agonist | experimental | Small molecule | PPARA agonist |
| lobeglitazone | Agonist | experimental | Small molecule | PPARA agonist |
| ly-518674 | Agonist | experimental | Small molecule | PPARA agonist |
| mk-0767 | Agonist | experimental | Small molecule | Peroxisome proliferator-activated receptor alpha agonist |
| mk0767 | Agonist | experimental | Small molecule | PPARA agonist |
| muraglitazar | Agonist | experimental | Small molecule | PPARA agonist |
| naveglitazar | Agonist | experimental | Small molecule | PPARA agonist |
| ono-5129 | Agonist | experimental | Small molecule | PPARA agonist |
| pemafibrate | Agonist | experimental | Small molecule | Peroxisome proliferator-activated receptor alpha agonist |
| saroglitazar | Agonist | experimental | Small molecule | Peroxisome proliferator-activated receptor alpha agonist |
| tesaglitazar | Agonist | experimental | Small molecule | PPARA agonist |
| zyh7 | Agonist | experimental | Small molecule | PPARA agonist |
| saroglitazar | Inhibitor | experimental | Small molecule | PPARA inhibitor |