← Mechanisms of action

TIGIT

SINGLE PROTEINHomo sapiens
Preferred name: T-cell immunoreceptor with Ig and ITIM domains ChEMBL ↗

Linked proteins

Drugs acting on this target (44)

Active Pharmaceutical Ingredient Mechanism Type Approval Status API Type Mechanism of Action
ab154AntagonistexperimentalmAbTIGIT antagonist
ab308AntagonistexperimentalmAbTIGIT
agen1777AntagonistexperimentalmAbTIGIT
ak127AntagonistexperimentalmAbTIGIT
ak130AntagonistexperimentalmAbTIGIT
asp8374AntagonistexperimentalmAbTIGIT antagonist
AZD2936AntagonistexperimentalmAbTIGIT
bat6005AntagonistexperimentalmAbTIGIT
bat6021AntagonistexperimentalmAbTIGIT
bgb-a1217AntagonistexperimentalmAbTIGIT antagonist
bms-986442AntagonistexperimentalmAbTIGIT
eos884448AntagonistexperimentalmAbTIGIT antagonist
hb0036AntagonistexperimentalmAbTIGIT
hlx301AntagonistexperimentalmAbTIGIT
hlx53AntagonistexperimentalRecombinant proteinTIGIT
ibi321AntagonistexperimentalmAbTIGIT
js006AntagonistexperimentalmAbTIGIT
ly3435151AntagonistexperimentalmAbTIGIT antagonist
omp-313m32AntagonistexperimentalmAbTIGIT antagonist
tiraglolumabAntagonistexperimentalmAbTIGIT
tiragolumabAntagonistexperimentalmAbTIGIT antagonist
vibostolimabAntagonistexperimentalmAbT-cell immunoreceptor with Ig and ITIM domains antagonist
zg005AntagonistexperimentalmAbTIGIT antagonist
ab154InhibitorexperimentalmAbT-cell immunoreceptor with Ig and ITIM domains inhibitor
bc008InhibitorexperimentalmAbTIGIT inhibitor
belrestotugInhibitorexperimentalmAbinhibitor - TIGIT
belrestotugInhibitorexperimentalmAbinhibitor - TIGIT
belrestotugInhibitorexperimentalmAbinhibitor - TIGIT
bgb-a1217InhibitorexperimentalmAbT-cell immunoreceptor with Ig and ITIM domains inhibitor
bms-986207InhibitorexperimentalmAbTIGIT inhibitor
com902InhibitorexperimentalmAbTIGIT inhibitor
hb0030InhibitorexperimentalmAbinhibitor - TIGIT
hy07121InhibitorexperimentalmAbTIGIT inhibitor
ibi939InhibitorexperimentalmAbTIGIT inhibitor
m6223InhibitorexperimentalmAbTIGIT inhibitor
omp-313m32InhibitorexperimentalmAbT-cell immunoreceptor with Ig and ITIM domains inhibitor
pm1009InhibitorexperimentalmAbinhibitor - TIGIT
pm1021InhibitorexperimentalmAbinhibitor - TIGIT
pm1022InhibitorexperimentalmAbinhibitor - TIGIT
sgn-tgtInhibitorexperimentalmAbTIGIT inhibitor
sh006InhibitorexperimentalmAbTIGIT inhibitor
sim0348InhibitorexperimentalmAbinhibitor - TIGIT
tiragolumabInhibitorexperimentalmAbT-cell immunoreceptor with Ig and ITIM domains inhibitor
vibostolimabInhibitorexperimentalmAbinhibitor - TIGIT