← Mechanisms of action
PLG
SINGLE PROTEINHomo sapiens
Preferred name: Plasminogen ChEMBL ↗
Linked proteins
Drugs acting on this target (17)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| alteplase (Activase) | Activator | approved | Recombinant protein | PLG activator |
| apsac | Activator | experimental | Recombinant protein | PLG activator |
| biib132 | Activator | experimental | Nucleic acid | PLG activator |
| defibrotide (defitelio) | Activator | approved | Animal product | PLG activator |
| Desmoteplase | Activator | experimental | Recombinant protein | PLG activator |
| dnase | Activator | experimental | Recombinant protein | PLG activator |
| lt3001 | Activator | experimental | Small molecule | PLG activator |
| reteplase (Retavase) | Activator | approved | Recombinant protein | PLG activator |
| saruplase | Activator | experimental | Recombinant protein | PLG activator |
| streptokinase (streptase) | Activator | approved | Biological | PLG activator |
| tenecteplase (tnkase) | Activator | approved | Recombinant protein | PLG activator |
| urokinase (kinlytic) | Activator | approved | Biological | PLG activator |
| plasminogen (Ryplazim) | Agonist | approved | Biological | PLG agonist |
| aminocaproic acid (amicar) | Inhibitor | approved | Small molecule | PLG inhibitor |
| aprotinin (trasylol) | Inhibitor | withdrawn | Small molecule | PLG inhibitor |
| bt-114143 | Inhibitor | experimental | Small molecule | PLG inhibitor |
| tranexamic acid (cyklokapron) | Inhibitor | approved | Small molecule | PLG inhibitor |