Esophageal Motility Disorders
Disorders affecting the motor function of the UPPER ESOPHAGEAL SPHINCTER; LOWER ESOPHAGEAL SPHINCTER; the ESOPHAGUS body, or a combination of these parts. The failure of the sphincters to maintain a tonic pressure may result in gastric reflux of food and acid into the esophagus (GASTROESOPHAGEAL REFLUX). Other disorders include hypermotility (spastic disorders) and markedly increased amplitude in contraction (nutcracker esophagus).
Subtype terms (5)
More specific conditions that are subtypes of Esophageal Motility Disorders in the MeSH hierarchy.
- CREST Syndrome
2 drugs (1 approved, 1 experimental)
- Esophageal Achalasia
22 drugs (17 approved, 5 experimental)
- Esophageal Spasm, Diffuse
2 drugs approved
- Gastroesophageal Reflux
152 drugs (63 approved, 89 experimental)
- Plummer-Vinson Syndrome
Drugs by status
Phase 4 trials (4)
Phase 3 trials (1)
Phase 2 trials (3)
Phase 1 trials (1)
Organizations
Organization Involved with Phase 4 Indications (1)
Organization Involved with Phase 2 Indications (4)
Organization Involved with Phase 1 Indications (1)