Hemoglobinuria

The presence of free HEMOGLOBIN in the URINE, indicating hemolysis of ERYTHROCYTES within the vascular system. After saturating the hemoglobin-binding proteins (HAPTOGLOBINS), free hemoglobin begins to appear in the urine.

Drugs by status

Approved for this indication (2)

eculizumab
ravulizumab-cwvz

Phase 2 trials (3)

prednisone
levamisole
cyclosporine

Organizations

Organization Involved with Phase 4 Indications (2)

Alexion
Chinese Academy of Medical Sciences

Organization Involved with Phase 3 Indications (14)

Regeneron
Amgen
Roche
Akari Therapeutics
Novartis
Biocad
Chugai
Apellis Pharmaceuticals, Inc.
National Heart, Lung, and Blood Institute (NHLBI)
Vilnius University
University of California, Los Angeles
Samsung
St. Jude Children's Hospital
AO GENERIUM

Organization Involved with Phase 2 Indications (14)

Achillion Pharmaceuticals
BioCryst
Alnylam Pharmaceuticals
Ra Pharmaceuticals
National Cancer Institute (NCI)
University of Arizona
Cornell University
Duke University
University of Washington
Indiana University
Radboud University
University of Naples Frederico II
State University of New York, Buffalo
CMIC Co, Ltd. Japan

Organization Involved with Phase 1 Indications (1)

Johns Hopkins University

Organization Involved with Other Experimental Indications (1)

University of Minnesota

ICD-10 crosswalk

R82.3 — Hemoglobinuria