clostridium butyricum

Cell therapyexperimental

Clostridium butyricum is a strictly anaerobic endospore-forming Gram-positive butyric acid–producing bacillus subsisting by means of fermentation using an intracellularly accumulated amylopectin-like α-polyglucan (granulose) as a substrate. It is uncommonly reported as a human pathogen and is widely used as a probiotic in Japan, Korea, and China. C. butyricum is a soil inhabitant in various parts of the world, has been cultured from the stool of healthy children and adults, and is common in soured milk and cheeses. The connection with dairy products is shown by the name, the butyr- in butyricum reflects the relevance of butyric acid in the bacteria's metabolism and the connection with Latin butyrum and Greek βούτυρον, with word roots pertaining to butter and cheese. — Wikipedia

Chemistry & pharmacology

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • clostridium butyricum
  • miya-bm

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT07037004Phase 2May 4, 2026City of Hope National Medical Center, National Cancer Institute (NCI)
NCT07263880Phase 1/Phase 2 (Phase 2)Dec 1, 2025Azienda Ospedaliera San Giovanni Addolorata, University of Roma La Sapienza
NCT07167342Phase 4Oct 31, 2025Dongying People's Hospital, Shandong, Jining NO.1 People 's Hospital, Linyi People's Hospital, People's Hospital of Rizhao, Qingdao University, Shandong first medical University, Shandong Province Qianfoshan Hospital, Shandong Provincial Hospital, Shandong University, Tai'an Central Hospital, Weifang People's Hospital
NCT07152886Phase 4Oct 31, 2025Dongying People's Hospital, Shandong, Jining NO.1 People 's Hospital, Linyi People's Hospital, People's Hospital of Rizhao, Qingdao University, Shandong first medical University, Shandong Province Qianfoshan Hospital, Shandong Provincial Hospital, Shandong University, Tai'an Central Hospital, Weifang People's Hospital
NCT07182890Phase 4Sep 20, 2025People's Liberation Army of China
NCT06676514N/ANov 10, 2024Liaquat University of Medical & Health Sciences, University of Urbino "Carlo Bo"
NCT06399419Phase 1Jun 19, 2024City of Hope National Medical Center, National Cancer Institute (NCI), Osel, Inc.
NCT06677840N/AMay 1, 2024National Taiwan University
NCT06696742Phase 2Feb 1, 2024Nanjing Medical University
NCT06548256N/AOct 31, 2023Kaohsiung Medical University
NCT05914389Phase 2Aug 31, 2023Zhejiang University
NCT06852274N/AMar 1, 2023Azienda Ospedaliera San Giovanni Addolorata, Liaquat University of Medical & Health Sciences
NCT05724511Phase 4Feb 27, 2023China Medical University
NCT05759741Early Phase 1 (Phase 1)Jan 17, 2023Fudan University
NCT05122546Phase 1Nov 1, 2021City of Hope National Medical Center, National Cancer Institute (NCI)
NCT04688242Phase 2Jan 1, 2021Sun Yat-Sen University
NCT05237115Phase 4May 5, 2020People's Liberation Army of China, Xijing Hospital
NCT03829111Phase 1May 14, 2019City of Hope National Medical Center, National Cancer Institute (NCI)
NCT03922035Phase 1Apr 18, 2019City of Hope National Medical Center, National Cancer Institute (NCI)
NCT03857425Phase 4Mar 1, 2019People's Liberation Army of China
Showing 20 of 28 trials
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Organizations

Research & Development (33)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
City of Hope National Medical CenterAcademic/Hospital5422019
National Cancer Institute (NCI)Government5022019
Shandong UniversityAcademic/Hospital4222014
Linyi People's HospitalAcademic/Hospital3012015
People's Liberation Army of ChinaGovernment3312019
Tai'an Central HospitalAcademic/Hospital3012015
Azienda Ospedaliera San Giovanni AddolorataAcademic/Hospital2122023
Dongying People's Hospital, ShandongAcademic/Hospital2012025
Jining NO.1 People 's HospitalAcademic/Hospital2012025
Kaohsiung Medical UniversityAcademic/Hospital2212017
Liaquat University of Medical & Health SciencesAcademic/Hospital2212023
Min-Sheng General HospitalAcademic/Hospital2212011
Osel, Inc.For profit2222010
People's Hospital of RizhaoAcademic/Hospital2012025
Qingdao UniversityAcademic/Hospital2212025
Shandong first medical UniversityAcademic/Hospital2012025
Shandong Province Qianfoshan HospitalAcademic/Hospital2012025
Shandong Provincial HospitalAcademic/Hospital2012025
Weifang People's HospitalAcademic/Hospital2012025
Chang Gung UniversityAcademic/Hospital1112014
33 organizations
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