wild-type reovirus
Vaccineexperimental
Clinical trial activity
10 trials · 7 clinical orgs · 0 marketing orgs
Phase 1
5
Phase 2
4
Phase 3
0
Phase 4
0
Earliest trial started Apr 1, 2008 (NCT00602277)
Timeline
Indications
Studied for
- Astrocytoma · Phase 1
- Brain Neoplasms · Phase 1
- Diffuse Intrinsic Pontine Glioma · Phase 1
- Fallopian Tube Neoplasms · Phase 2
- Glioblastoma · Phase 1
- Glioma · Phase 1
- Hamartoma · Phase 2
- Immunoglobulin Light Chains · Phase 1
- Medulloblastoma · Phase 1
- Melanoma · Phase 2
- Multiple Myeloma · Phase 1
- Neoplasms · Phase 1
- Neuroectodermal Tumors · Phase 1
- Oligodendroglioma · Phase 1
- Ovarian Neoplasms · Phase 2
- Pancreatic Neoplasms · Phase 2
- Rhabdoid Tumor · Phase 1
Mechanism of action
- Reovirus sp.Immunity, active
Reovirus sp. immunity, active
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Also known as
- wild-type reovirus
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT03723915 | Phase 2 | Nov 14, 2018 | National Cancer Institute (NCI), Northwestern University |
| NCT02514382 | Phase 1 | Aug 21, 2015 | National Cancer Institute (NCI), Oncolytics Biotech, University of Southern California |
| NCT02444546 | Phase 1 | Jun 1, 2015 | Mayo Clinic, National Cancer Institute (NCI) |
| NCT02101944 | N/A | Sep 25, 2014 | National Cancer Institute (NCI), Ohio State University |
| NCT01533194 | Phase 1 | Apr 1, 2012 | National Cancer Institute (NCI), Ohio State University |
| NCT01199263 | Phase 2 | Dec 6, 2010 | National Cancer Institute (NCI), NRG Oncology |
| NCT01280058 | Phase 2 | Dec 1, 2010 | National Cancer Institute (NCI), Ohio State University |
| NCT01240538 | Phase 1 | Dec 1, 2010 | National Cancer Institute (NCI) |
| NCT00602277 | Phase 1 | Apr 1, 2008 | National Cancer Institute (NCI), Ohio State University |
| NCT00651157 | Phase 2 | Apr 1, 2008 | Mayo Clinic, National Cancer Institute (NCI) |
Showing 10 of 10 trials
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Organizations
Research & Development (7)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| National Cancer Institute (NCI) | Government | 10 | 7 | 3 | 2008 |
| Ohio State University | Academic/Hospital | 4 | 0 | 3 | 2008 |
| Mayo Clinic | Academic/Hospital | 2 | 1 | 2 | 2008 |
| Northwestern University | Academic/Hospital | 1 | 1 | 1 | 2018 |
| NRG Oncology | Academic/Hospital | 1 | 0 | 1 | 2010 |
| Oncolytics Biotech | For profit | 1 | 0 | 1 | 2015 |
| University of Southern California | Academic/Hospital | 1 | 1 | 1 | 2015 |
7 organizations
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