Tiratricol
Trade name: triacana
Small moleculeexperimental
Clinical trial activity
4 trials · 7 clinical orgs · 0 marketing orgs
Phase 1
0
Phase 2
3
Phase 3
1
Phase 4
0
Earliest trial started Oct 1, 2014 (NCT02060474)
Timeline
Indications
Mechanism of action
- Thyroid hormone receptorAGONIST
Thyroid hormone receptor agonist
- Unspecified targetUnclear
unclear
Chemistry & pharmacology
Loading structure…
SMILES
O=C(O)Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1- Mol. weight
- 621.93 g/mol
- Lipinski Ro5
- 1 violation(s)
- Rule of 3
- No
- Chirality
- Achiral Molecule
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL41632 ↗
Also known as
- 3,3',5-triiodothyroacetic acid
- 3',3,5-triiodothyroacetic acid
- 3',3,5-triiodothyroacetic acid
- 3,3',5-triiodothyroacetic acid, sodium salt
- 3,5,3'-triiodothyroacetic acid
- 3,5-diiodo-3'-isopropylthyroacetic acid
- 4-(4-hydroxy-3-iodophenoxy)-3,5-diiodobenzeneacetic acid
- téatrois
- tiratricol
- tiratricol
- tiratricol
- tiratricol
- tiratricol
- tiratricol
- tiratricol
- tiratricol
- tiratricolum
- tiratricolum
- triac
- triac
- triac
- triacana
- triacana
- triacana
- triacana
- triiodothyroacetic acid
- triiodothyroacetic acid
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT05579327 | Phase 3 | Nov 30, 2022 | Egetis Therapeutics, Erasmus University Rotterdam, Premier Research Group, Rare Thyroid Therapeutics International AB, University of Pennsylvania |
| NCT02396459 | Phase 2 | Jul 1, 2016 | Erasmus University Rotterdam |
| NCT02060474 | Phase 2 | Oct 1, 2014 | Erasmus University Rotterdam, ZonMw: The Netherlands Organisation for Health Research and Development |
| NCT05911399 | N/A | — | AnovoRx, Egetis Therapeutics, Rare Thyroid Therapeutics International AB |
Showing 4 of 4 trials
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Organizations
Research & Development (7)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Erasmus University Rotterdam | Academic/Hospital | 3 | 2 | 2 | 2014 |
| Egetis Therapeutics | For profit | 2 | 0 | 2 | 2022 |
| Rare Thyroid Therapeutics International AB | For profit | 2 | 2 | 2 | 2022 |
| AnovoRx | For profit | 1 | 0 | 1 | — |
| Premier Research Group | For profit | 1 | 0 | 1 | 2022 |
| University of Pennsylvania | Academic/Hospital | 1 | 0 | 1 | 2022 |
| ZonMw: The Netherlands Organisation for Health Research and Development | Academic/Hospital | 1 | 0 | 1 | 2014 |
7 organizations
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