revexepride
Small moleculeexperimental
Clinical trial activity
4 trials · 4 clinical orgs · 0 marketing orgs
Phase 1
2
Phase 2
2
Phase 3
0
Phase 4
0
Earliest trial started Dec 1, 2010 (NCT01370863)
Timeline
Indications
Mechanism of action
- Serotonin 4 (5-HT4) receptorAGONIST
HTR4 agonist
Chemistry & pharmacology
Loading structure…
SMILES
COCCCN1CC[C@@H](CNC(=O)c2cc(Cl)c(N)c3c2OC(C)(C)C3)[C@H](O)C1- Mol. weight
- 425.96 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL3545035 ↗
Also known as
- revexepride
- revexepride
- revexepride
- spd557
- spd-557
- spd-557
- ssp-002358
- ssp-002358
- ssp-002358
- ssp-002358
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT01786876 | Phase 1 | Feb 1, 2013 | Covance, Shire |
| NCT01472939 | Phase 2 | Feb 1, 2012 | Shire |
| NCT01415349 | Phase 1 | Aug 1, 2011 | Shire |
| NCT01370863 | Phase 2 | Dec 1, 2010 | Katholieke Universiteit Leuven, Movetis, Shire |
Showing 4 of 4 trials
Page 1 / 1
Organizations
Research & Development (4)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Shire | For profit | 4 | 4 | 2 | 2010 |
| Covance | For profit | 1 | 0 | 1 | 2013 |
| Katholieke Universiteit Leuven | Academic/Hospital | 1 | 0 | 1 | 2010 |
| Movetis | For profit | 1 | 0 | 1 | 2010 |
4 organizations
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