senicapoc

Small moleculeexperimental

Senicapoc (ICA-17043) is a Gardos channel blocker. — Wikipedia

Clinical trial activity

11 trials · 14 clinical orgs · 0 marketing orgs

Phase 1
1
Phase 2
10
Phase 3
3
Phase 4
0

Earliest trial started Feb 1, 2002 (NCT00040677)

Timeline

2000s

  1. Jan 1, 2002

    Earliest Phase 2 Sponsor(trial)

  2. Jan 1, 2005

    Earliest Phase 3 Sponsor(trial)

2020s

  1. Jan 1, 2026

    Earliest Phase 1 Sponsor(trial)

Indications

Mechanism of action

Chemistry & pharmacology

Loading structure…

SMILES

NC(=O)C(c1ccccc1)(c1ccc(F)cc1)c1ccc(F)cc1
Mol. weight
323.34 g/mol
Lipinski Ro5
Pass
Rule of 3
No
Chirality
Achiral Molecule
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • bis(4-fluorophenyl)phenylacetamide
  • ica17043
  • ica 17043
  • ica-17043
  • ica-17043
  • ica-17043
  • ica-17043
  • pf-05416266
  • pf-05416266
  • senicapoc
  • senicapoc
  • senicapoc
  • senicapoc

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT07284069Early Phase 1 (Phase 1)Feb 1, 2026Aarhus University, University of Copenhagen
NCT07282210Phase 2Jan 31, 2026Biossil Inc.
NCT06714123Phase 2Jan 31, 2025Region Syddanmark, University of Southern Denmark
NCT04804241Phase 2Jan 1, 2022University of California, Davis
NCT04372498Phase 3Jul 1, 2020Harvard University, Quest Diagnostics
NCT04594668Phase 2Apr 24, 2020Aalborg University, Aarhus University, University of Copenhagen, University of Southern Denmark
NCT00861185Phase 2Mar 1, 2009ICAgen
NCT00861211Phase 2Oct 1, 2008ICAgen, University of London
NCT00294541Phase 3Feb 1, 2006ICAgen, Johnson and Johnson
NCT00102791Phase 3Feb 1, 2005ICAgen, McNeil
NCT00040677Phase 2Feb 1, 2002ICAgen, University of North Carolina at Chapel Hill
Showing 11 of 11 trials
Page 1 / 1

Organizations

Research & Development (14)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
ICAgenFor profit5522002
Aarhus UniversityAcademic/Hospital2222020
University of CopenhagenAcademic/Hospital2022020
University of Southern DenmarkAcademic/Hospital2012020
Aalborg UniversityAcademic/Hospital1012020
Biossil Inc.For profit1112026
Harvard UniversityAcademic/Hospital1112020
Johnson and JohnsonFor profit1012006
McNeilFor profit1012005
Quest DiagnosticsFor profit1012020
Region SyddanmarkAcademic/Hospital1112025
University of California, DavisAcademic/Hospital1112022
University of LondonAcademic/Hospital1012008
University of North Carolina at Chapel HillAcademic/Hospital1012002
14 organizations
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