modified vaccinia ankara-5t4 vaccine
Vaccineexperimental
TroVax is a cancer vaccine that was developed by Oxford BioMedica. No cancer vaccines have been proven to cure cancer or extend life yet, TroVax has been studied in a number of trials for colon cancer. — Wikipedia
Clinical trial activity
8 trials · 14 clinical orgs · 0 marketing orgs
Phase 1
0
Phase 2
8
Phase 3
1
Phase 4
0
Earliest trial started Jun 1, 2004 (NCT00259844)
Timeline
Indications
Mechanism of action
- Trophoblast glycoproteinImmunity, active
TPBG immunity, active
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaTroVax ↗
Also known as
- modified vaccinia ankara-5t4 vaccine
- trovax
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT01556841 | Phase 2 | Nov 1, 2013 | Cancer Research UK, Oxford BioMedica, University of London |
| NCT01569919 | Phase 2 | Dec 1, 2012 | Cardiff University, June Hancock Mesothelioma Research Fund, Velindre NHS Trust |
| NCT00397345 | Phase 3 | Sep 1, 2006 | Oxford BioMedica |
| NCT00445523 | Phase 2 | May 1, 2006 | Baylor University, Methodist Cancer Center, Houston, Texas, Oxford BioMedica |
| NCT00448409 | Phase 2 | May 1, 2006 | Methodist Cancer Center, Houston, Texas, Oxford BioMedica, The University of Texas, Dallas |
| NCT00325507 | Phase 2 | Nov 1, 2005 | Methodist Cancer Center, Houston, Texas, ORION Clinical Services, Oxford BioMedica |
| NCT00227474 | Phase 2 | Sep 26, 2005 | National Cancer Institute (NCI), Southwest Oncology Group, University of Washington |
| NCT00259844 | Phase 2 | Jun 1, 2004 | Cancer Research UK, Oxford BioMedica, The Christie NHS Foundation Trust |
Showing 8 of 8 trials
Page 1 / 1
Organizations
Research & Development (14)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Oxford BioMedica | For profit | 6 | 2 | 2 | 2004 |
| Methodist Cancer Center, Houston, Texas | Academic/Hospital | 3 | 2 | 1 | 2005 |
| Cancer Research UK | Academic/Hospital | 2 | 1 | 1 | 2004 |
| Baylor University | Academic/Hospital | 1 | 0 | 1 | 2006 |
| Cardiff University | Academic/Hospital | 1 | 1 | 1 | 2012 |
| June Hancock Mesothelioma Research Fund | Academic/Hospital | 1 | 0 | 1 | 2012 |
| National Cancer Institute (NCI) | Government | 1 | 0 | 1 | 2005 |
| ORION Clinical Services | For profit | 1 | 0 | 1 | 2005 |
| Southwest Oncology Group | Academic/Hospital | 1 | 1 | 1 | 2005 |
| The Christie NHS Foundation Trust | Academic/Hospital | 1 | 0 | 1 | 2004 |
| The University of Texas, Dallas | Academic/Hospital | 1 | 0 | 1 | 2006 |
| University of London | Academic/Hospital | 1 | 1 | 1 | 2013 |
| University of Washington | Academic/Hospital | 1 | 0 | 1 | 2005 |
| Velindre NHS Trust | Academic/Hospital | 1 | 0 | 1 | 2012 |
14 organizations
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