← Mechanisms of action
TPBG
SINGLE PROTEINHomo sapiens
Preferred name: Trophoblast glycoprotein ChEMBL ↗
Linked proteins
Drugs acting on this target (19)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| pf-06263507 | Binding agent | experimental | mAb | Trophoblast glycoprotein binding agent |
| durvalumab (imfinzi) | Cross-linking agent | approved | mAb | TPBG cross-linking agent |
| bb-mpi-03 | Immunity, active | experimental | Vaccine | TPBG immunity, active |
| chadox1-mva 5t4 | Immunity, active | experimental | Vaccine | TPBG immunity, active |
| modified vaccinia ankara-5t4 vaccine | Immunity, active | experimental | Vaccine | TPBG immunity, active |
| anti-5t4 car-rank cells | Immunity, passive | experimental | Cell therapy | TPBG immunity, passive |
| ibr854 | Immunity, passive | experimental | Cell therapy | immunity, passive - 5T4 |
| alg.apv-527 | Inhibitor | experimental | mAb | TPBG inhibitor |
| asn004 | Inhibitor | experimental | mAb | TPBG inhibitor |
| cba-1535 | Inhibitor | experimental | mAb | TPBG inhibitor |
| ftl008.16 | Inhibitor | experimental | mAb | TPBG inhibitor |
| gen1044 | Inhibitor | experimental | mAb | TPBG inhibitor |
| jk06 | Inhibitor | experimental | mAb | TPBG inhibitor |
| naptumomab estafenatox | Inhibitor | experimental | mAb | TPBG inhibitor |
| pf-06263507 | Inhibitor | experimental | mAb | TPBG inhibitor |
| syd1875 | Inhibitor | experimental | mAb | TPBG inhibitor |
| tub-030 | Inhibitor | experimental | mAb | TPBG inhibitor |
| xb010 | Inhibitor | experimental | mAb | TPBG inhibitor |
| naptumomab estafenatox | Other | experimental | mAb | TPBG other |