qbw251

Small moleculeexperimental

Clinical trial activity

13 trials · 7 clinical orgs · 0 marketing orgs

Phase 1
4
Phase 2
8
Phase 3
3
Phase 4
0

Earliest trial started Jul 1, 2012 (NCT02190604)

Timeline

2010s

  1. Jan 1, 2012

    Earliest Phase 2 Sponsor(trial)

2020s

  1. Jan 1, 2020

    Earliest Phase 1 Sponsor(trial)

  2. Jan 1, 2022

    Earliest Phase 3 Sponsor(trial)

Indications

Mechanism of action

Chemistry & pharmacology

Loading structure…

SMILES

COc1nc(C(=O)NC[C@](C)(O)C(F)(F)F)c(N)cc1C(F)(F)F
Mol. weight
361.24 g/mol
Lipinski Ro5
Pass
Rule of 3
No
Chirality
Single Stereoisomer
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • qbw251
  • qbw251
  • qbw-251

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT06259526Phase 2Dec 26, 2023Tasly Pharmaceuticals, Inc.
NCT06125327Phase 2/Phase 3 (Phase 3)Jun 6, 2023Government of China
NCT07030504Phase 1Jan 10, 2023Shenzhen Salubris Pharmaceuticals Co., Ltd., Shenzhen University
NCT06135363Phase 1Aug 11, 2022Government of China
NCT05604170Phase 3May 16, 2022Marinus Pharmaceuticals
NCT05323734Phase 3Apr 1, 2022Marinus Pharmaceuticals
NCT06160440Phase 1Jun 3, 2021Government of China
NCT04396366Phase 2Nov 30, 2020European Commission, Novartis
NCT04587622Phase 1Oct 30, 2020Novartis
NCT04268823Phase 2Mar 23, 2020Novartis
NCT04072887Phase 2Sep 23, 2019Novartis
NCT02449018Phase 2Apr 1, 2015Novartis
NCT02190604Phase 2Jul 1, 2012Novartis
Showing 13 of 13 trials
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Organizations

Research & Development (7)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
NovartisFor profit6622012
Government of ChinaGovernment3322021
Marinus PharmaceuticalsFor profit2212022
European CommissionGovernment1012020
Shenzhen Salubris Pharmaceuticals Co., Ltd.For profit1112023
Shenzhen UniversityAcademic/Hospital1012023
Tasly Pharmaceuticals, Inc.For profit1112023
7 organizations
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