indeglitazar
Small moleculeexperimental
Plexxikon is an American drug discovery company based in South San Francisco, California. It was co-founded in 2001 by Joseph Schlessinger of Yale University, and Sung-Hou Kim of the University of California, Berkeley. — Wikipedia
Clinical trial activity
3 trials · 2 clinical orgs · 0 marketing orgs
Phase 1
2
Phase 2
1
Phase 3
0
Phase 4
0
Earliest trial started Nov 1, 2006 (NCT00448032)
Timeline
Indications
Studied for
Mechanism of action
Peroxisome proliferator-activated receptor agonist
Ph2 study terminated due to safety concerns
Chemistry & pharmacology
Loading structure…
SMILES
COc1ccc(S(=O)(=O)n2cc(CCC(=O)O)c3cc(OC)ccc32)cc1- Mol. weight
- 389.43 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Achiral Molecule
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaPlexxikon ↗
- ChEMBLCHEMBL1232583 ↗
Also known as
- indeglitazar
- indeglitazar
- indeglitazar
- ppm-204
- ppm-204
- ppm-204
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT00425919 | Phase 2 | Jan 1, 2007 | Pfizer, Wyeth |
| NCT00447629 | Phase 1 | Jan 1, 2007 | Pfizer, Wyeth |
| NCT00448032 | Phase 1 | Nov 1, 2006 | Pfizer, Wyeth |
Showing 3 of 3 trials
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