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plx-7486

Small moleculeexperimental

Clinical trial activity

1 trials · 1 clinical orgs · 0 marketing orgs

Phase 1

1

Phase 2

0

Phase 3

0

Phase 4

0

Earliest trial started Aug 1, 2013 (NCT01804530)

Timeline

2010s

Jan 1, 2013
Earliest Phase 1 Sponsor(trial)

Indications

Studied for

Mechanism of action

NT-3 growth factor receptorINHIBITOR
NTRK3 inhibitor
- NT-3 growth factor receptor (NTRK3) ↗
Neurotrophic tyrosine kinase receptor type 2INHIBITOR
NTRK2 inhibitor
- BDNF/NT-3 growth factors receptor (NTRK2) ↗
Nerve growth factor receptor Trk-AINHIBITOR
NTRK1 inhibitor
- High affinity nerve growth factor receptor (NTRK1) ↗
Macrophage colony stimulating factor receptorINHIBITOR
CSF1R inhibitor
- Macrophage colony-stimulating factor 1 receptor (CSF1R) ↗

Chemistry & pharmacology

Chirality: Single Stereoisomer
Inorganic: No
Polymer: No

Oral

No

Parenteral

No

Topical

No

Sources

ChEMBLCHEMBL3545381 ↗

Also known as

plx7486
plx-7486

Clinical trials

NCT ID	Phase	Start date	Sponsor(s)
NCT01804530	Phase 1	Aug 1, 2013	Plexxikon

Showing 1 of 1 trials

Page 1 / 1

Organizations

Research & Development (1)

Organization	Org type	Trials	As lead sponsor	Phases	Earliest year
Plexxikon	For profit	1	1	1	2013

1 organizations

Page 1 / 1