mirikizumab

Trade name: Omvoh

mAbapproved

Approved

Oct 26, 2023

Mirikizumab, sold under the brand name Omvoh, is a monoclonal antibody used for the treatment of ulcerative colitis. It is designed to attach to interleukin-23 (IL-23) and block its activity. — Wikipedia

Clinical trial activity

44 trials · 8 clinical orgs · 1 marketing orgs

Phase 1
17
Phase 2
21
Phase 3
15
Phase 4
6

Earliest trial started Oct 1, 2013 (NCT01947933)

Timeline

2010s

  1. Jan 1, 2013

    Eli Lilly — Earliest Phase 1 Sponsor(trial)

  2. Jan 1, 2015

    Eli Lilly — Earliest Phase 2 Sponsor(trial)

  3. Jan 1, 2018

    Eli Lilly — Earliest Phase 3 Sponsor(trial)

2020s

  1. Oct 26, 2023

    Eli Lilly — Earliest FDA Approval

  2. Oct 26, 2023

    Eli Lilly — Marketing Organization

  3. Oct 26, 2023

    Eli Lilly — NDA Organization

Indications

Mechanism of action

Approval history

  • approvedOct 26, 2023

Chemistry & pharmacology

Chirality
Single Stereoisomer
Inorganic
No
Polymer
No
Delivery
Parenteral
Availability
Prescription Only
Multi-specific
No

Oral

No

Parenteral

Yes

Topical

No

Sources

Also known as

  • ly3074828
  • mirikizumab

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT06997965Phase 4Feb 1, 2026Robarts Clinical Trials
NCT07292012Phase 4Jan 31, 2026Groupe d'Etude Therapeutique des Affections Inflammatoires Digestives (GETAID), University Clermont Auvergne
NCT07235904Phase 4Nov 30, 2025Universitaetsklinikum Schleswig-Holstein
NCT07186101Phase 2Nov 11, 2025Eli Lilly
NCT07059130Phase 4Jul 16, 2025Eli Lilly, Rubix LS
NCT06937099Phase 3Jun 26, 2025Eli Lilly
NCT06937086Phase 3Jun 26, 2025Eli Lilly
NCT06864403Phase 4Apr 30, 2025Eli Lilly, University of North Carolina at Chapel Hill
NCT06598943Phase 2Oct 10, 2024Eli Lilly
NCT06626165Phase 4Jul 20, 2024Showa Inan General Hospital
NCT06475729Phase 1Jun 24, 2024Eli Lilly
NCT05784246Phase 3Oct 26, 2023Eli Lilly
NCT05767021Phase 3May 17, 2023Eli Lilly
NCT05509777Phase 3Dec 9, 2022Eli Lilly
NCT05644353Phase 1Dec 5, 2022Eli Lilly
NCT05515601Phase 1Aug 31, 2022Eli Lilly
NCT05069896Phase 1Oct 5, 2021Eli Lilly
NCT04844606Phase 3May 26, 2021Eli Lilly
NCT04469062Phase 3Apr 20, 2021Eli Lilly
NCT04607733Phase 1Nov 2, 2020Eli Lilly
Showing 20 of 44 trials
Page 1 / 3

Organizations

Research & Development (8)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
Eli LillyFor profit403842013
Groupe d'Etude Therapeutique des Affections Inflammatoires Digestives (GETAID)Academic/Hospital1112026
Robarts Clinical TrialsFor profit1112026
Rubix LSFor profit1112025
Showa Inan General HospitalAcademic/Hospital1112024
Universitaetsklinikum Schleswig-HolsteinAcademic/Hospital1112025
University Clermont AuvergneAcademic/Hospital1012026
University of North Carolina at Chapel HillAcademic/Hospital1112025
8 organizations
Page 1 / 1

Marketing (2)

OrganizationOrg typeRelationshipDate
Eli LillyFor profitMKTGOct 26, 2023
Eli LillyFor profitNDAOct 26, 2023