← Mechanisms of action
IL12B
SINGLE PROTEINHomo sapiens
Preferred name: Interleukin-12 subunit beta ChEMBL ↗
Linked proteins
Drugs acting on this target (33)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| xmab662 | Activator | experimental | mAb | IL12B activator |
| abo2011 | Agonist | experimental | Small molecule | IL12B agonist |
| medi1191 | Agonist | experimental | Nucleic acid | IL12B agonist |
| ak101 | Inhibitor | experimental | mAb | IL12B inhibitor |
| as1409 | Inhibitor | experimental | mAb | IL12B inhibitor |
| briakinumab | Inhibitor | experimental | mAb | IL12B inhibitor |
| kgx101 | Inhibitor | experimental | Small molecule | IL12B inhibitor |
| ustekinumab (stelara) | Inhibitor | approved | mAb | IL12B inhibitor |
| ad-rts-hil-12 | Supplementation | experimental | Gene therapy | IL12B supplementation |
| ad.hil-12 | Supplementation | experimental | Gene therapy | IL12B supplementation |
| adenovirus-mediated human interleukin-12 | Supplementation | experimental | Gene therapy | IL12B supplementation |
| ank-101 | Supplementation | experimental | Recombinant protein | IL12B supplementation |
| cln-617 | Supplementation | experimental | Recombinant protein | IL12B supplementation |
| df6002 | Supplementation | experimental | Recombinant protein | IL12B supplementation |
| human single chain il-12 mrna-multiple dose | Supplementation | experimental | Nucleic acid | IL12B supplementation |
| il-12 dna | Supplementation | experimental | Vaccine | IL12B supplementation |
| il-12 dna plasmids | Supplementation | experimental | Gene therapy | IL12B supplementation |
| imnn-001 | Supplementation | experimental | Gene therapy | IL12B supplementation |
| ino-9112 | Supplementation | experimental | Vaccine | IL12B supplementation |
| interleukin-12 | Supplementation | experimental | Recombinant protein | IL12B supplementation |
| interleukin-12 dna | Supplementation | experimental | Gene therapy | IL12B supplementation |
| jcxh-211 | Supplementation | experimental | Nucleic acid | IL12B supplementation |
| jcxh-213 | Supplementation | experimental | Gene therapy | IL12B supplementation |
| m9241 | Supplementation | experimental | Recombinant protein | IL12B supplementation |
| pcx-12 | Supplementation | experimental | Nucleic acid | IL12B supplementation |
| peg-pei-cholesterol lipopolymer-encased il-12 dna plasmid vector gen-1 | Supplementation | experimental | Gene therapy | IL12B supplementation |
| phil12 | Supplementation | experimental | Gene therapy | IL12B supplementation |
| stx-001 | Supplementation | experimental | Nucleic acid | IL12B supplementation |
| tavokinogene telseplasmid | Supplementation | experimental | Gene therapy | IL12B supplementation |
| veledimex | Supplementation | experimental | Gene therapy | IL12B supplementation |
| vrp-encapsulated sarna encoding il-12 | Supplementation | experimental | Biological | IL12B supplementation |
| wtx-330 | Supplementation | experimental | Recombinant protein | IL12B supplementation |
| xtx301 | Supplementation | experimental | Recombinant protein | IL12B supplementation |