← Mechanisms of action
IL23A
SINGLE PROTEINHomo sapiens
Preferred name: Interleukin-23 subunit alpha ChEMBL ↗
Linked proteins
Drugs acting on this target (15)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| hs-20137 | Antagonist | experimental | mAb | IL23A antagonist |
| IL-23/CGRP bispecific antibody | Antagonist | experimental | mAb | IL23A antagonist |
| mirikizumab (Omvoh) | Antagonist | approved | mAb | IL23A antagonist |
| pn-232 | Antagonist | experimental | Small molecule | IL23A antagonist |
| ak101 | Inhibitor | experimental | mAb | IL23A inhibitor |
| brazikumab | Inhibitor | experimental | mAb | IL23A inhibitor |
| gr2303 | Inhibitor | experimental | mAb | IL23A inhibitor |
| guselkumab (tremfya) | Inhibitor | approved | mAb | IL23A inhibitor |
| jnj-86974680 | Inhibitor | experimental | Peptide | IL23A inhibitor |
| sor102 | Inhibitor | experimental | Small molecule | IL23A inhibitor |
| spy003 | Inhibitor | experimental | mAb | IL23A inhibitor |
| tildrakizumab (Ilumetri) | Inhibitor | approved | mAb | IL23A inhibitor |
| ustekinumab (stelara) | Inhibitor | approved | mAb | IL23A inhibitor |
| il-23 | Supplementation | experimental | Recombinant protein | IL23A supplementation |
| interleukin 23 | Supplementation | experimental | Recombinant protein | IL23A supplementation |