CDEK
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Olinciguat

Small moleculeexperimental

Clinical trial activity

6 trials · 2 clinical orgs · 0 marketing orgs

Phase 1
4
Phase 2
2
Phase 3
0
Phase 4
0

Earliest trial started Oct 1, 2015 (NCT02572349)

Timeline

2010s

  1. Jan 1, 2015

    Earliest Phase 1 Sponsor(trial)

  2. Jan 1, 2016

    Earliest Phase 2 Sponsor(trial)

Indications

Studied for

Mechanism of action

Chemistry & pharmacology

Loading structure…

SMILES

NC(=O)[C@](O)(CNc1nc(-c2cc(-c3ccon3)n(Cc3ccccc3F)n2)ncc1F)C(F)(F)F
Mol. weight
509.4 g/mol
Lipinski Ro5
1 violation(s)
Rule of 3
No
Chirality
Single Stereoisomer
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • iw-1701

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT03892499Phase 1May 3, 2019Cyclerion Therapeutics, Inc.
NCT03795519Phase 1Jan 17, 2019Cyclerion Therapeutics, Inc., Ironwood Pharmaceuticals
NCT03285178Phase 2Dec 22, 2017Ironwood Pharmaceuticals
NCT02792998Phase 1May 1, 2016Ironwood Pharmaceuticals
NCT02931565Phase 2Feb 1, 2016Ironwood Pharmaceuticals
NCT02572349Phase 1Oct 1, 2015Ironwood Pharmaceuticals
Showing 6 of 6 trials
Page 1 / 1

Organizations

Research & Development (2)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
Ironwood PharmaceuticalsFor profit5422015
Cyclerion Therapeutics, Inc.For profit2212019
2 organizations
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