CDEK
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tanezumab

mAbexperimental

Tanezumab is a monoclonal antibody against nerve growth factor as a treatment for pain via a novel mechanisms different from conventional pain-killer drugs. Tanezumab was discovered and developed by Rinat Neuroscience and was acquired by Pfizer in 2006. — Wikipedia

Clinical trial activity

38 trials · 51 clinical orgs · 0 marketing orgs

Phase 1
3
Phase 2
35
Phase 3
20
Phase 4
0

Earliest trial started Mar 1, 2006 (NCT00394563)

Timeline

2000s

  1. Jan 1, 2006

    Earliest Phase 2 Sponsor(trial)

  2. Jan 1, 2008

    Earliest Phase 1 Sponsor(trial)

  3. Jan 1, 2008

    Earliest Phase 3 Sponsor(trial)

Indications

Studied for

Mechanism of action

Chemistry & pharmacology

Chirality
Single Stereoisomer
Inorganic
No
Polymer
No
Multi-specific
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • anti-ngf ab
  • pf04383119
  • pf 04383119
  • pf-04383119
  • pf-04383119
  • pf-04383119
  • pf4383119
  • pf 4383119
  • pf-4383119
  • pf-4383119
  • ri 624
  • ri-624
  • ri624 mab
  • rn624
  • rn624
  • rn 624
  • rn-624
  • rn624 mab
  • tanezumab
  • tanezumab
  • tanezumab
  • tanezumab

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT04163419Phase 2Feb 29, 2020Harvard University, Pfizer
NCT03031938Phase 3Oct 31, 2017Eli Lilly, Pfizer
NCT02725411Phase 3May 26, 2016Pfizer
NCT02709486Phase 3Mar 2, 2016Eli Lilly, Pfizer
NCT02697773Phase 3Jan 21, 2016Pfizer
NCT02609828Phase 3Oct 28, 2015Albert Einstein Israelite Hospital, Ambulancia Klinickej onkologie FNsP Nove Zamky, Bajcsy-Zsilinszky Hospital, Ballarat Health Services, Biovirtus, Complexo Hospitalario Universitario de A Coruña, Departmental Hosptital of Vendee, Eli Lilly, Faculdade de Medicina do ABC, Flinders University, Fundacao Antonio Prudente, Fundacion Favaloro Para La Docencia e Investigacion Medica, Hallym University, Hetenyi G Korhaz, Hospicjum im. Ks. Eugeniusza Dutkiewicza SAC w Gdansku, Hospital de Cancer de Barretos - Fundacao Pio XII, Hospital Sanitas La Moraleja, Hospital Universitario Fundación Alcorcón, Instituto de Oncologia de Rosario, Instituto do Cancer do Estado de São Paulo, Keimyung University, Klinikum Klagenfurt, L'Hospitalet de Llobregat, Masarykuv onkologicky ustav, Klinika komplexni onkologicke pece, Monash University, National Institutes of Health (NIH), Nemocnice Horovice, Niepliczny Zakad Opieki Zdrowotnej Zespo Medyczno-Opieku-Czy Alicja Kluczna, Nishinomiya Municipal Central Hospital, Nuhr Medical Center, Oncocenter Onclogie Clinica S.R.L, Oncolab SRL, Oncology department of Nemocnice Benesov, Pfizer, Polyclinique de L'ormeau, Poradnia Medycyny Paliatywnej Hospicjum Palium, Powiatowy Zespo Zakadow Opieki Zdrowotnej w Bdzinie, Oddzia Opieki Paliatywnej Szpital Czelad, Sanera, s.r.o., Seoul National University, Slovak Research Center, Stowarzyszenie Przyjacio Chorych Hospicjum, Sue Ryder Home, Sungkyunkwan University, The National Cancer Center, Universidad Autonoma de Madrid, University Alicante, University of Edinburgh, Velindre NHS Trust, Wilhelminenspital der Stadt Wien, Yonsei University
NCT02528253Phase 3Aug 18, 2015Eli Lilly, Pfizer
NCT02528188Phase 3Jul 21, 2015Pfizer
NCT01146561Phase 2Oct 1, 2010Pfizer
NCT01127893Phase 3Jun 1, 2010Pfizer
NCT01089725Phase 3Mar 1, 2010Pfizer
NCT01087203Phase 2Mar 1, 2010Pfizer
NCT00960804Phase 3Feb 1, 2010Pfizer
NCT00999518Phase 2Jan 1, 2010Pfizer
NCT01030640Phase 1Dec 1, 2009Pfizer
NCT00994890Phase 2Nov 1, 2009Pfizer
NCT00830180Phase 2Oct 1, 2009Pfizer
NCT00985621Phase 3Oct 1, 2009Pfizer
NCT00864097Phase 3Aug 1, 2009Pfizer
NCT00924664Phase 2/Phase 3 (Phase 3)Aug 1, 2009Pfizer
Showing 20 of 38 trials
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Organizations

Research & Development (51)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
PfizerFor profit383732006
Eli LillyFor profit4012015
Albert Einstein Israelite HospitalAcademic/Hospital1012015
Ambulancia Klinickej onkologie FNsP Nove ZamkyAcademic/Hospital1012015
Bajcsy-Zsilinszky HospitalAcademic/Hospital1012015
Ballarat Health ServicesAcademic/Hospital1012015
BiovirtusFor profit1012015
Complexo Hospitalario Universitario de A CoruñaAcademic/Hospital1012015
Departmental Hosptital of VendeeAcademic/Hospital1012015
Faculdade de Medicina do ABCAcademic/Hospital1012015
Flinders UniversityAcademic/Hospital1012015
Fundacao Antonio PrudenteAcademic/Hospital1012015
Fundacion Favaloro Para La Docencia e Investigacion MedicaAcademic/Hospital1012015
Hallym UniversityAcademic/Hospital1012015
Harvard UniversityAcademic/Hospital1112020
Hetenyi G KorhazAcademic/Hospital1012015
Hospicjum im. Ks. Eugeniusza Dutkiewicza SAC w GdanskuAcademic/Hospital1012015
Hospital de Cancer de Barretos - Fundacao Pio XIIAcademic/Hospital1012015
Hospital Sanitas La MoralejaAcademic/Hospital1012015
Hospital Universitario Fundación AlcorcónAcademic/Hospital1012015
51 organizations
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