ethiodized oil
Trade name: ethiodol
Small moleculeapproved
Approved
Mar 31, 1954
Iodized oil, also known as ethiodized oil, brand name Lipiodol, is a medication derived from poppyseed oil and iodine. When given by injection, it is a radio-opaque contrast agent that is used to outline structures in radiological investigations. When given orally or by intramuscular injection once or twice a year, it prevents endemic goitre in remote communities. It has an additional use in gastric variceal obliteration as a dilutant that does not affect polymerization of cyanoacrylate. — Wikipedia
Clinical trial activity
10 trials · 15 clinical orgs · 1 marketing orgs
Phase 1
3
Phase 2
8
Phase 3
5
Phase 4
0
Earliest trial started Jun 1, 2001 (NCT00027768)
Timeline
Indications
Approved for
Studied for
- Carcinoma, Hepatocellular · Phase 3
- Carcinoma, Non-Small-Cell Lung · Phase 2
- Colonic Neoplasms · Phase 2
- Fertilization in Vitro · Phase 3
- Head and Neck Neoplasms · Phase 1
- Liver Neoplasms · Phase 3
- Lung Neoplasms · Early Phase 1
- Mediastinal Neoplasms · Phase 2
- Melanoma · Phase 2
- Neoplasm Metastasis · Phase 2
- Osteoarthritis, Knee · Phase 3
- Pleural Neoplasms · Phase 2
- Sarcoma · Phase 2
Mechanism of action
- Unspecified targetOTHER
Diagnostic agent
- UnclearUnclear
Unclear unclear
Approval history
- approvedPriority reviewMar 31, 1954
Chemistry & pharmacology
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
- Delivery
- Topical
- Availability
- Prescription Only
Oral
No
Parenteral
No
Topical
Yes
Black box warning
Sources
- WikipediaIodized oil ↗
- NCATSKZW0R0686Q ↗
- ChEMBLCHEMBL1201458 ↗
- WikipediaLipiodol ↗
Also known as
- eoe 13
- eoe 13
- eoe-13
- ethiodiol
- ethiodized oil
- ethiodized oil
- ethiodized oil
- ethiodized oil
- ethiodized oil
- ethiodized oil emulsion 13
- ethiodol
- ethiodol
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT06497140 | Phase 3 | Sep 30, 2024 | Assistance Publique - Hôpitaux de Paris, Government of France |
| NCT06130072 | Phase 3 | Nov 10, 2023 | Ain Shams University |
| NCT05672108 | Phase 2 | May 12, 2023 | City of Hope National Medical Center, National Cancer Institute (NCI) |
| NCT05490381 | Phase 1 | Jan 5, 2023 | Guerbet, University of Washington |
| NCT05435014 | Phase 1/Phase 2 (Phase 2) | Sep 13, 2022 | T-ACE Medical Co., Ltd |
| NCT04728633 | Phase 2 | Sep 27, 2021 | Thomas Jefferson University |
| NCT04753918 | Early Phase 1 (Phase 1) | Mar 31, 2021 | Taoyan County Governmnet, Taiwan, Taoyuan General Hospital |
| NCT01966133 | Phase 3 | Aug 1, 2011 | Fudan University |
| NCT00870558 | Phase 3 | Jun 1, 2005 | CHU Edouard Herriot, University of Lyon |
| NCT00027768 | Phase 3 | Jun 1, 2001 | Government of Singapore |
Showing 10 of 10 trials
Page 1 / 1
Organizations
Research & Development (15)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Ain Shams University | Academic/Hospital | 1 | 1 | 1 | 2023 |
| Assistance Publique - Hôpitaux de Paris | Academic/Hospital | 1 | 1 | 1 | 2024 |
| CHU Edouard Herriot | Academic/Hospital | 1 | 0 | 1 | 2005 |
| City of Hope National Medical Center | Academic/Hospital | 1 | 1 | 1 | 2023 |
| Fudan University | Academic/Hospital | 1 | 1 | 1 | 2011 |
| Government of France | Government | 1 | 0 | 1 | 2024 |
| Government of Singapore | Government | 1 | 1 | 1 | 2001 |
| Guerbet | For profit | 1 | 0 | 1 | 2023 |
| National Cancer Institute (NCI) | Government | 1 | 0 | 1 | 2023 |
| T-ACE Medical Co., Ltd | For profit | 1 | 1 | 1 | 2022 |
| Taoyan County Governmnet, Taiwan | Government | 1 | 0 | 1 | 2021 |
| Taoyuan General Hospital | Academic/Hospital | 1 | 1 | 1 | 2021 |
| Thomas Jefferson University | Academic/Hospital | 1 | 1 | 1 | 2021 |
| University of Lyon | Academic/Hospital | 1 | 1 | 1 | 2005 |
| University of Washington | Academic/Hospital | 1 | 1 | 1 | 2023 |
15 organizations
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