il-7
Recombinant proteinexperimental
Interleukin 7 (IL-7) is a protein that in humans is encoded by the IL7 gene. — Wikipedia
Clinical trial activity
29 trials · 30 clinical orgs · 0 marketing orgs
Phase 1
16
Phase 2
17
Phase 3
0
Phase 4
0
Earliest trial started Apr 1, 2003 (NCT00062049)
Timeline
Indications
Studied for
- Antigens, CD · Phase 1/Phase 2
- Breast Neoplasms · Phase 2
- Carcinoma, Transitional Cell · Phase 2
- Castration · Phase 2
- Colorectal Neoplasms · Phase 1
- Cord Blood Stem Cell Transplantation · Phase 1
- COVID-19 · Phase 2
- Hepatitis C · Phase 1/Phase 2
- HIV · Phase 2
- HIV Infections · Phase 2
- Kidney Neoplasms · Phase 1
- Leukemia, Myelogenous, Chronic, BCR-ABL Positive · Phase 1
- Leukemia, Myeloid, Acute · Phase 1
- Lymphoma, B-Cell · Phase 2
- Lymphopenia · Phase 2
- Melanoma · Phase 1
- Multiple Myeloma · Phase 1
- Mycobacterium Infections, Nontuberculous · Phase 2
- Myelodysplastic Syndromes · Phase 1
- Myeloproliferative Disorders · Phase 1
- Neoplasms · Phase 1
- Neuroblastoma · Phase 1/Phase 2
- Neuroectodermal Tumors, Primitive, Peripheral · Phase 1/Phase 2
- Prostatic Neoplasms · Phase 2
- Prostatic Neoplasms, Castration-Resistant · Phase 2
- Rhabdomyosarcoma, Alveolar · Phase 1/Phase 2
- Rhabdomyosarcoma, Embryonal · Phase 1/Phase 2
- Sarcoma · Phase 1/Phase 2
- Sepsis · Phase 2
- Ureteral Neoplasms · Phase 2
- Urethral Neoplasms · Phase 2
- Urinary Bladder Neoplasms · Phase 2
Mechanism of action
- Interleukin-7Supplementation
Interleukin-7 supplementation
Chemistry & pharmacology
- Inorganic
- No
- Polymer
- No
- Multi-specific
- No
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaInterleukin 7 ↗
- ChEMBLCHEMBL4297772 ↗
Also known as
- il-7
- il-7
- interleukin-7
- interleukin-7
- recombinant human interleukin-7
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT06523699 | Phase 1 | Oct 31, 2024 | Accentia Biopharmaceuticals, Washington University in St. Louis |
| NCT05600920 | Phase 1/Phase 2 (Phase 2) | Dec 29, 2022 | National Institute of Allergy and Infectious Diseases (NIAID) |
| NCT04927169 | Phase 2 | Mar 1, 2021 | Accentia Biopharmaceuticals, Federal University of Sao Paulo, ReSolution Latin America S.A. |
| NCT04501796 | Phase 1 | Aug 31, 2020 | NeoImmuneTech, Inc. |
| NCT04407689 | Phase 2 | Jun 1, 2020 | Accentia Biopharmaceuticals, Amarex Clinical Research, University of Limoges |
| NCT04379076 | Phase 2 | May 14, 2020 | Accentia Biopharmaceuticals, Amarex Clinical Research, University of London |
| NCT04154826 | Phase 2 | Jan 6, 2020 | Accentia Biopharmaceuticals, Washington University in St. Louis |
| NCT04054752 | Phase 1 | Aug 16, 2019 | National Cancer Institute (NCI), NeoImmuneTech, Inc. |
| NCT03941769 | Phase 1 | Jul 31, 2019 | National Cancer Institute (NCI), University of Texas at Houston |
| NCT03929107 | Phase 2 | Mar 28, 2019 | Zhejiang University |
| NCT03513952 | Phase 2 | Sep 30, 2018 | Cancer Immunotherapy Trials Network, National Cancer Institute (NCI) |
| NCT02640807 | Phase 2 | Jan 1, 2016 | Accentia Biopharmaceuticals, Vanderbilt University, Washington University in St. Louis |
| NCT02797431 | Phase 2 | Jan 1, 2016 | Accentia Biopharmaceuticals, University of Limoges, Vanderbilt University |
| NCT02659800 | N/A | Nov 1, 2015 | Accentia Biopharmaceuticals, Johns Hopkins University, National Cancer Institute (NCI) |
| NCT01881867 | Phase 2 | Mar 1, 2015 | Cancer Immunotherapy Trials Network, National Cancer Institute (NCI), University of Washington |
| NCT01368107 | Phase 2 | Jun 1, 2011 | Centre Leon Berard, Cytheris, Government of France |
| NCT01019551 | Phase 2 | Sep 1, 2010 | Cytheris, Merck, Objectif Recherche Vaccins SIDA, Pfizer, University of California, San Francisco |
| NCT01190111 | Phase 2 | Jan 1, 2010 | Case Western Reserve University, Cytheris |
| NCT01024894 | Phase 1/Phase 2 (Phase 2) | Jan 1, 2009 | Cytheris, Kaohsiung Medical University |
| NCT01025297 | Phase 1/Phase 2 (Phase 2) | Jul 1, 2008 | Cantonal Hospital of St. Gallen, Cytheris |
Showing 20 of 29 trials
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Organizations
Research & Development (30)
30 organizations
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