CDEK
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fluzoparib

Small moleculeexperimental

Clinical trial activity

93 trials · 33 clinical orgs · 0 marketing orgs

Phase 1
31
Phase 2
71
Phase 3
13
Phase 4
0

Earliest trial started Apr 1, 2015 (NCT02575651)

Timeline

2010s

  1. Jan 1, 2015

    Earliest Phase 1 Sponsor(trial)

  2. Jan 1, 2018

    Earliest Phase 2 Sponsor(trial)

  3. Jan 1, 2019

    Earliest Phase 3 Sponsor(trial)

Indications

Studied for

Mechanism of action

Chemistry & pharmacology

Loading structure…

SMILES

O=C(c1cc(Cc2n[nH]c(=O)c3ccccc23)ccc1F)N1CCn2nc(C(F)(F)F)nc2C1
Mol. weight
472.4 g/mol
Lipinski Ro5
Pass
Rule of 3
No
Chirality
Achiral Molecule
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • fluzoparib
  • shr3162

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT07141771Phase 1/Phase 2 (Phase 2)Dec 31, 2025Chinese Academy of Medical Sciences
NCT07047066Phase 2Jul 10, 2025Huazhong University of Science and Technology
NCT07033819Phase 2Jun 25, 2025Chinese Academy of Medical Sciences
NCT06954584Phase 3May 27, 2025Huazhong University of Science and Technology
NCT06827717Phase 2Apr 15, 2025Hengrui Therapeutics, Inc., Sun Yat-Sen University
NCT06913777Phase 3Apr 8, 2025Fudan University
NCT06188455Phase 3Dec 1, 2024Xiamen University
NCT06971211Phase 2Nov 27, 2024China Medical University
NCT06735326Phase 2Nov 27, 2024Shandong University
NCT06539091Phase 3Oct 1, 2024Anhui Medical University, Anhui Province Cancer Hospital
NCT06552858Phase 2Sep 1, 2024Fudan University
NCT06612814Phase 3Sep 1, 2024China Medical University, Chongqing Medical University, Dalian Medical University, Fudan University, Fujian Medical University, Jiao Tong University, Nanjing Medical University, Nantong University, Ningbo Medical Center Lihuili Eastern Hospital, Peking University, Sun Yat-Sen University
NCT06561022Phase 2Aug 21, 2024Fudan University
NCT06533384Phase 3Aug 1, 2024Shantou University
NCT06446206Phase 2Jun 30, 2024Jinlin University
NCT06541314Phase 2Jun 18, 2024Shandong University
NCT06413992Phase 2May 10, 2024Chinese Academy of Medical Sciences
NCT06254066Phase 2Apr 16, 2024Chinese Academy of Medical Sciences, Hengrui Therapeutics, Inc.
NCT06255392Phase 3Feb 29, 2024Sun Yat-Sen University
NCT06208410Phase 1/Phase 2 (Phase 2)Jan 11, 2024Risen (Suzhou) Pharma Tech Co., Ltd.
Showing 20 of 93 trials
Page 1 / 5

Organizations

Research & Development (33)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
Hengrui Therapeutics, Inc.For profit362942015
Fudan UniversityAcademic/Hospital171722018
Sun Yat-Sen UniversityAcademic/Hospital10822022
Peking UniversityAcademic/Hospital7232015
Chinese Academy of Medical SciencesAcademic/Hospital6522019
Central South UniversityAcademic/Hospital4122019
Chongqing Medical UniversityAcademic/Hospital4222022
Fujian Medical UniversityAcademic/Hospital4222022
Jiao Tong UniversityAcademic/Hospital4132020
Tianjin Medical UniversityAcademic/Hospital4422018
China Medical UniversityAcademic/Hospital3122023
Dalian Medical UniversityAcademic/Hospital3122022
Huazhong University of Science and TechnologyAcademic/Hospital3322023
Nanjing Medical UniversityAcademic/Hospital3122023
Shandong UniversityAcademic/Hospital3322021
Atridia Pty Ltd.For profit2212016
Nantong UniversityAcademic/Hospital2022023
Ningbo Medical Center Lihuili Eastern HospitalAcademic/Hospital2022023
People's Liberation Army of ChinaGovernment2012015
Anhui Medical UniversityAcademic/Hospital1112024
33 organizations
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