ef5
Small moleculeexperimentalImaging agent
Clinical trial activity
16 trials · 9 clinical orgs · 0 marketing orgs
Phase 1
8
Phase 2
5
Phase 3
0
Phase 4
0
Earliest trial started Mar 1, 1998 (NCT00003282)
Timeline
Indications
Studied for
- Astrocytoma · Phase 1
- Brain Neoplasms · Phase 1
- Breast Neoplasms · Phase 1
- Carcinoma, Non-Small-Cell Lung · Phase 2
- Choroid Plexus Neoplasms · Phase 1
- Craniopharyngioma · Phase 1
- Endometrial Neoplasms · Phase 2
- Ependymoma · Phase 1
- Glioblastoma · Phase 1
- Glioma · Phase 1
- Gliosarcoma · Phase 1
- Hamartoma · Phase 2
- Head and Neck Neoplasms · Phase 2
- Lung Neoplasms · Phase 2
- Medulloblastoma · Phase 1
- Melanoma · Phase 1
- Meninges · Phase 1
- Meningioma · Phase 1
- Neoplasms · Phase 1
- Neoplasms, Germ Cell and Embryonal · Phase 1
- Neuroectodermal Tumors · Phase 1
- Oligodendroglioma · Phase 1
- Ovarian Neoplasms · Phase 2
- Prostatic Neoplasms · Phase 1
- Sarcoma · Phase 1
- Squamous Cell Carcinoma of Head and Neck · Phase 2
- Uterine Cervical Neoplasms · Phase 2
Mechanism of action
- Unspecified targetRadiopharmaceutical
radiopharmaceutical
Chemistry & pharmacology
- Imaging
- 18-fluorine
Oral
No
Parenteral
No
Topical
No
Also known as
- 18f ef5
- 18f ef5
- 18f-ef5
- 18f-ef5
- ef5
- ef5
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT01774760 | Phase 2 | Mar 1, 2013 | University of Turku |
| NCT01752257 | Phase 1 | Jul 1, 2012 | Duke University, Varian Medical Systems |
| NCT01163487 | Phase 1 | Aug 1, 2010 | Stanford University |
| NCT01055678 | Early Phase 1 (Phase 1) | Jan 1, 2010 | Duke University, National Cancer Institute (NCI), National Institutes of Health (NIH) |
| NCT01017133 | Phase 1 | May 1, 2009 | University of Pennsylvania |
| NCT00978874 | Phase 1 | May 1, 2008 | National Cancer Institute (NCI), University of Pennsylvania |
| NCT00110032 | Phase 1 | Jun 1, 2005 | National Cancer Institute (NCI), University of Pennsylvania |
| NCT00107445 | Phase 2 | Feb 1, 2005 | National Cancer Institute (NCI), University of Pennsylvania |
| NCT00087191 | N/A | May 1, 2004 | National Cancer Institute (NCI), University of Pennsylvania |
| NCT00049231 | N/A | Jun 1, 2003 | Gynecologic Oncology Group, National Cancer Institute (NCI), University of Toronto |
| NCT00049140 | Phase 2 | Aug 1, 2002 | Duke University, National Cancer Institute (NCI) |
| NCT02154399 | Phase 2 | May 1, 2002 | Duke University, National Cancer Institute (NCI) |
| NCT00041028 | Phase 2 | May 1, 2002 | Duke University, National Cancer Institute (NCI) |
| NCT00896961 | N/A | Aug 1, 2001 | National Cancer Institute (NCI), University of Pennsylvania |
| NCT00004261 | Phase 1 | Dec 1, 1999 | National Cancer Institute (NCI), University of Toronto |
| NCT00003282 | Phase 1 | Mar 1, 1998 | National Cancer Institute (NCI), University of Pennsylvania |
Showing 16 of 16 trials
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Organizations
Research & Development (9)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| National Cancer Institute (NCI) | Government | 12 | 6 | 3 | 1998 |
| University of Pennsylvania | Academic/Hospital | 7 | 2 | 3 | 1998 |
| Duke University | Academic/Hospital | 5 | 4 | 2 | 2002 |
| University of Toronto | Academic/Hospital | 2 | 1 | 2 | 1999 |
| Gynecologic Oncology Group | Academic/Hospital | 1 | 1 | 1 | 2003 |
| National Institutes of Health (NIH) | Government | 1 | 0 | 1 | 2010 |
| Stanford University | Academic/Hospital | 1 | 1 | 1 | 2010 |
| University of Turku | Academic/Hospital | 1 | 1 | 1 | 2013 |
| Varian Medical Systems | For profit | 1 | 0 | 1 | 2012 |
9 organizations
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