cyt107
Small moleculeexperimental
Clinical trial activity
9 trials · 12 clinical orgs · 0 marketing orgs
Phase 1
4
Phase 2
8
Phase 3
0
Phase 4
0
Earliest trial started Mar 1, 2008 (NCT00684008)
Timeline
Indications
Studied for
- Cord Blood Stem Cell Transplantation · Phase 1/Phase 2
- COVID-19 · Phase 2
- Hepatitis B, Chronic · Phase 1/Phase 2
- HIV · Phase 2
- Leukemia, Myelogenous, Chronic, BCR-ABL Positive · Phase 1
- Leukemia, Myeloid, Acute · Phase 1
- Lymphopenia · Phase 2
- Myelodysplastic Syndromes · Phase 1
- Sepsis · Phase 2
- T-Lymphocytopenia, Idiopathic CD4-Positive · Phase 1/Phase 2
Mechanism of action
- PAC1-PAC2 complexSupplementation
PAC1-PAC2 complex supplementation
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Also known as
- cyt107
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT07308886 | Phase 2 | Jan 5, 2026 | National Cancer Institute (NCI) |
| NCT04442178 | Phase 2 | Sep 15, 2020 | Accentia Biopharmaceuticals, Amarex Clinical Research, Washington University in St. Louis |
| NCT04426201 | Phase 2 | Jun 22, 2020 | Accentia Biopharmaceuticals, Amarex Clinical Research, Memorial Sloan-Kettering Cancer Center |
| NCT03821038 | Phase 2 | Mar 31, 2019 | Accentia Biopharmaceuticals, George Clinical Pty Ltd, University of Limoges, Washington University in St. Louis |
| NCT03600896 | Phase 1/Phase 2 (Phase 2) | Nov 30, 2018 | Accentia Biopharmaceuticals, National Cancer Institute (NCI), University of Texas at Houston |
| NCT01241643 | Phase 2 | Sep 1, 2010 | Cytheris |
| NCT01027065 | Phase 1/Phase 2 (Phase 2) | Dec 1, 2009 | Cytheris, University of Bologna |
| NCT00839436 | Phase 1/Phase 2 (Phase 2) | Feb 1, 2009 | National Institute of Allergy and Infectious Diseases (NIAID) |
| NCT00684008 | Phase 1 | Mar 1, 2008 | Cornell University, Cytheris |
Showing 9 of 9 trials
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Organizations
Research & Development (12)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Accentia Biopharmaceuticals | For profit | 4 | 3 | 1 | 2018 |
| Cytheris | For profit | 3 | 3 | 2 | 2008 |
| Amarex Clinical Research | For profit | 2 | 0 | 1 | 2020 |
| National Cancer Institute (NCI) | Government | 2 | 1 | 1 | 2018 |
| Washington University in St. Louis | Academic/Hospital | 2 | 0 | 1 | 2019 |
| Cornell University | Academic/Hospital | 1 | 0 | 1 | 2008 |
| George Clinical Pty Ltd | Academic/Hospital | 1 | 0 | 1 | 2019 |
| Memorial Sloan-Kettering Cancer Center | Academic/Hospital | 1 | 0 | 1 | 2020 |
| National Institute of Allergy and Infectious Diseases (NIAID) | Government | 1 | 1 | 1 | 2009 |
| University of Bologna | Academic/Hospital | 1 | 0 | 1 | 2009 |
| University of Limoges | Academic/Hospital | 1 | 0 | 1 | 2019 |
| University of Texas at Houston | Academic/Hospital | 1 | 1 | 1 | 2018 |
12 organizations
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