bpn14770

Small moleculeexperimental

Clinical trial activity

14 trials · 6 clinical orgs · 0 marketing orgs

Phase 1
8
Phase 2
5
Phase 3
3
Phase 4
0

Earliest trial started Dec 1, 2015 (NCT02648672)

Timeline

2010s

  1. Jan 1, 2015

    Earliest Phase 1 Sponsor(trial)

  2. Jan 1, 2018

    Earliest Phase 2 Sponsor(trial)

2020s

  1. Jan 1, 2022

    Earliest Phase 3 Sponsor(trial)

Indications

Mechanism of action

Chemistry & pharmacology

Loading structure…

SMILES

OC(=O)CC1=CC=C(CC2=CC(=NC(=C2)C(F)(F)F)C3=CC=CC(Cl)=C3)C=C1
Mol. weight
405.798 g/mol
Lipinski Ro5
1 violation(s)
Rule of 3
No
Chirality
Achiral Molecule
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • bpn14770

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT07018492Phase 1Aug 30, 2025Shionogi
NCT07012005Phase 1Aug 25, 2025Shionogi
NCT07011992Phase 1Jul 18, 2025Shionogi
NCT06717438Phase 2Jan 31, 2025Shionogi
NCT05367960Phase 3Sep 30, 2022Rush University, Tetra Discovery Partners
NCT05358886Phase 3Jun 30, 2022Rush University, Tetra Discovery Partners
NCT05163808Phase 2/Phase 3 (Phase 3)Dec 15, 2021Tetra Discovery Partners
NCT04044781Phase 1Oct 31, 2019Cornell University, Tetra Discovery Partners
NCT03817684Phase 2Apr 30, 2019Tetra Discovery Partners
NCT03861000Phase 1Mar 12, 2019National Institute of Mental Health (NIMH)
NCT03569631Phase 2Jun 25, 2018Tetra Discovery Partners
NCT03030105Phase 1Jan 1, 2017ICON, Tetra Discovery Partners
NCT02840279Phase 1Jun 1, 2016Tetra Discovery Partners
NCT02648672Phase 1Dec 1, 2015Tetra Discovery Partners
Showing 14 of 14 trials
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Organizations

Research & Development (6)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
Tetra Discovery PartnersFor profit9932015
ShionogiFor profit4422025
Rush UniversityAcademic/Hospital2012022
Cornell UniversityAcademic/Hospital1012019
ICONFor profit1012017
National Institute of Mental Health (NIMH)Government1112019
6 organizations
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