Branebrutinib

Small moleculeexperimental

Clinical trial activity

15 trials · 2 clinical orgs · 0 marketing orgs

Phase 1
11
Phase 2
4
Phase 3
0
Phase 4
0

Earliest trial started Sep 1, 2014 (NCT02257151)

Timeline

2010s

  1. Jan 1, 2014

    Earliest Phase 1 Sponsor(trial)

  2. Jan 1, 2016

    Earliest Phase 2 Sponsor(trial)

Indications

Mechanism of action

Chemistry & pharmacology

Loading structure…

SMILES

CC#CC(=O)N[C@H]1CCCN(c2c(F)cc(C(N)=O)c3[nH]c(C)c(C)c23)C1
Mol. weight
370.43 g/mol
Lipinski Ro5
Pass
Rule of 3
No
Chirality
Single Stereoisomer
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • bms-986142
  • bms-986142
  • bms-986195

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT05303220Phase 1Apr 8, 2022Bristol-Myers Squibb
NCT05014438Phase 2Aug 16, 2021Bristol-Myers Squibb
NCT04515628Phase 1Aug 17, 2020Bristol-Myers Squibb
NCT04186871Phase 2Dec 3, 2019Bristol-Myers Squibb
NCT03262740Phase 1Sep 11, 2017Bristol-Myers Squibb
NCT03245515Phase 1Aug 15, 2017Bristol-Myers Squibb
NCT03131973Phase 1May 13, 2017Bristol-Myers Squibb
NCT02843659Phase 2Oct 18, 2016Bristol-Myers Squibb
NCT02705989Phase 1Aug 18, 2016Bristol-Myers Squibb
NCT02880670Phase 1Aug 1, 2016Bristol-Myers Squibb
NCT02832180Phase 1May 1, 2016Bristol-Myers Squibb
NCT02762123Phase 1May 1, 2016Bristol-Myers Squibb
NCT02638948Phase 2Feb 16, 2016Bristol-Myers Squibb
NCT02456844Phase 1May 1, 2015Bristol-Myers Squibb, PPD
NCT02257151Phase 1Sep 1, 2014Bristol-Myers Squibb
Showing 15 of 15 trials
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Organizations

Research & Development (2)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
Bristol-Myers SquibbFor profit151522014
PPDFor profit1012015
2 organizations
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