CD3E

SINGLE PROTEINHomo sapiens

Preferred name: T-cell surface glycoprotein CD3 epsilon chain ChEMBL ↗

Linked proteins

T-cell surface glycoprotein CD3 epsilon chain (CD3E) ↗

Drugs acting on this target (231)

Active Pharmaceutical Ingredient	Mechanism Type ▲	Approval Status	API Type	Mechanism of Action
abbv-184	Activator	experimental	mAb	CD3E activator
abbv-243	Activator	experimental	mAb	CD3E activator
abo2203	Activator	experimental	mAb	CD3E activator
afm11	Activator	experimental	mAb	CD3E activator
alps12	Activator	experimental	mAb	CD3E activator
amg 211	Activator	experimental	mAb	CD3E activator
amg 305	Activator	experimental	mAb	CD3E activator
amg 330	Activator	experimental	mAb	CD3E activator
asp2138	Activator	experimental	mAb	CD3E activator
azd4360	Activator	experimental	mAb	CD3E activator
azd5492	Activator	experimental	mAb	CD3E activator
azd5863	Activator	experimental	mAb	CD3E activator
azd6621	Activator	experimental	mAb	CD3E activator
ba1202	Activator	experimental	mAb	CD3E activator
ba3182	Activator	experimental	mAb	CD3E activator
bcd-248	Activator	experimental	mAb	CD3E activator
bgb-b455	Activator	experimental	mAb	CD3E activator
bi 836909	Activator	experimental	mAb	CD3E activator
bite-ev	Activator	experimental	mAb	CD3E activator
blinatumomab (blincyto)	Activator	approved	mAb	CD3E activator
bms-986528	Activator	experimental	mAb	CD3E activator
br115	Activator	experimental	mAb	CD3E activator
catumaxomab (Removab)	Activator	experimental	mAb	CD3E activator
cba-1535	Activator	experimental	mAb	CD3E activator
cbi-1214	Activator	experimental	mAb	CD3E activator
cc312	Activator	experimental	mAb	CD3E activator
cdr404	Activator	experimental	mAb	CD3E activator
cln-978	Activator	experimental	mAb	CD3E activator
clsp-1025	Activator	experimental	mAb	CD3E activator
cm-336	Activator	experimental	mAb	CD3E activator
cm336	Activator	experimental	mAb	CD3E activator
CM350	Activator	experimental	mAb	CD3E
cnd261	Activator	experimental	mAb	CD3E activator
ctim-76	Activator	experimental	mAb	CD3E activator
duvortuxizumab	Activator	experimental	mAb	CD3E activator
Elranatamab (Elrexfio)	Activator	approved	mAb	CD3E activator
Epcoritamab (Epkinly)	Activator	approved	mAb	CD3E activator
ertumaxomab	Activator	experimental	mAb	CD3E activator
ery974	Activator	experimental	mAb	CD3E activator
ex103	Activator	experimental	mAb	CD3E activator
f182112	Activator	experimental	mAb	CD3E activator
fbta05	Activator	experimental	mAb	CD3E activator
Flotetuzumab	Activator	experimental	mAb	CD3E activator
gb261	Activator	experimental	mAb	CD3E activator
gbr 1302	Activator	experimental	mAb	CD3E activator
gen3017	Activator	experimental	mAb	CD3E activator
glofitamab (Columvi)	Activator	approved	mAb	CD3E activator
gnc-077	Activator	experimental	mAb	CD3E activator
gprc5d/cd3 bites	Activator	experimental	mAb	CD3E activator
gr1803	Activator	experimental	mAb	CD3E activator
gsk5458514	Activator	experimental	mAb	CD3E activator
hy05350	Activator	experimental	mAb	CD3E activator
igm-2644	Activator	experimental	mAb	CD3E activator
imc-p115c	Activator	experimental	mAb	CD3E activator
imc-r117c	Activator	experimental	mAb	CD3E activator
inca036873	Activator	experimental	mAb	CD3E activator
isb 2001	Activator	experimental	mAb	CD3E activator
janx007	Activator	experimental	mAb	CD3E activator
jnj-63709178	Activator	experimental	mAb	CD3E activator
jnj-75348780	Activator	experimental	mAb	CD3E activator
jnj-79635322	Activator	experimental	mAb	CD3E activator
jnj-80948543	Activator	experimental	mAb	CD3E activator
jnj-87801493	Activator	experimental	mAb	CD3E activator
jnj-87890387	Activator	experimental	mAb	CD3E activator
js203	Activator	experimental	mAb	CD3E activator
lava-1207	Activator	experimental	mAb	CD3E activator
lbl-033	Activator	experimental	mAb	CD3E activator
lnf2007	Activator	experimental	mAb	CD3E activator
lp-001	Activator	experimental	mAb	CD3E activator
ly4152199	Activator	experimental	mAb	CD3E activator
mbs303	Activator	experimental	mAb	CD3E activator
mbs314	Activator	experimental	mAb	CD3E activator
mcla-117	Activator	experimental	mAb	CD3E activator
mdx2001	Activator	experimental	mAb	CD3E activator
mdx2003	Activator	experimental	mAb	CD3E activator
mdx2004	Activator	experimental	mAb	CD3E activator
medi-565	Activator	experimental	mAb	CD3E activator
mgd007	Activator	experimental	mAb	CD3E activator
mgd009	Activator	experimental	mAb	CD3E activator
mor209	Activator	experimental	mAb	CD3E
msc303	Activator	experimental	mAb	CD3E activator
mt110	Activator	experimental	mAb	CD3E activator
muromonab cd3 (Orthoclone OKT3)	Activator	approved	mAb	CD3E activator
ni-0401	Activator	experimental	mAb	CD3E activator
nilk-2301	Activator	experimental	mAb	CD3E activator
nm32-2668	Activator	experimental	mAb	CD3E activator
om336	Activator	experimental	mAb	CD3E activator
pit565	Activator	experimental	Small molecule	CD3E activator
qls7305	Activator	experimental	mAb	CD3E activator
resimmune	Activator	experimental	mAb	CD3E activator
ro7444973	Activator	experimental	Recombinant protein	CD3E activator
ro7617991	Activator	experimental	mAb	CD3E activator
sctb35	Activator	experimental	mAb	CD3E activator
sim0500	Activator	experimental	mAb	CD3E activator
smet12	Activator	experimental	mAb	CD3E activator
soa101	Activator	experimental	mAb	CD3E activator
star0602	Activator	experimental	Recombinant protein	CD3E activator
tak-280	Activator	experimental	mAb	CD3E activator
Talquetamab (Talvey)	Activator	approved	mAb	CD3E activator
tgi-6	Activator	experimental	mAb	CD3E activator
tqb2029	Activator	experimental	mAb	CD3E activator
vnx-101	Activator	experimental	Gene therapy	CD3E activator
vnx-202	Activator	experimental	mAb	CD3E activator
wvt078	Activator	experimental	Cell therapy	CD3E activator
xmab541	Activator	experimental	mAb	CD3E activator
yk012	Activator	experimental	mAb	CD3E activator
ykst02	Activator	experimental	mAb	CD3E activator
zw171	Activator	experimental	mAb	CD3E activator
ro7616789	Adcc	experimental	mAb	CD3E adcc
A-337	Agonist	experimental	mAb	CD3E agonist
abbv-383	Agonist	experimental	mAb	CD3E
AMG-910	Agonist	experimental	mAb	CD3E
arb202	Agonist	experimental	mAb	cd3e
bay2010112	Agonist	experimental	mAb	CD3E
bi 765049	Agonist	experimental	mAb	CD3E
BIS-1	Agonist	experimental	mAb	CD3E
btrc4017a	Agonist	experimental	mAb	CD3E
cc-1	Agonist	experimental	mAb	CD3E agonist
cc-3	Agonist	experimental	mAb	CD3E agonist
cd33*cd3 bsab	Agonist	experimental	mAb	CD3E
cln-049	Agonist	experimental	mAb	CD3E
cm355	Agonist	experimental	mAb	CD3E
cx-904	Agonist	experimental	mAb	CD3E
emb-06	Agonist	experimental	mAb	CD3E
emb07	Agonist	experimental	mAb	CD3E
fbta05	Agonist	experimental	mAb	CD3E
gen1047	Agonist	experimental	mAb	CD3E
gnc-035	Agonist	experimental	mAb	CD3E
gnc-038	Agonist	experimental	mAb	CD3E agonist
gnc-039	Agonist	experimental	mAb	CD3E
hegfrviii-cd3	Agonist	experimental	mAb	CD3E
ima401	Agonist	experimental	mAb	CD3E agonist
jnj-78278343	Agonist	experimental	mAb	CD3E
jnj-78306358	Agonist	experimental	mAb	CD3E
mgd020	Agonist	experimental	mAb	CD3e
mgd024	Agonist	experimental	mAb	CD3E
mor209	Agonist	experimental	mAb	CD3E
mosunetuzumab (Lunsumio)	Agonist	approved	mAb	CD3E agonist
MVC-101	Agonist	experimental	mAb	CD3E
nivatrotamab	Agonist	experimental	mAb	CD3E agonist
NVG-111	Agonist	experimental	mAb	CD3E
oc-tr	Agonist	experimental	mAb	CD3E
pf-07260437	Agonist	experimental	mAb	CD3E
qls31904	Agonist	experimental	mAb	CD3e
qls31905	Agonist	experimental	mAb	cd3e
regn4336	Agonist	experimental	mAb	CD3E
rg 6007	Agonist	experimental	mAb	CD3E
sar442257	Agonist	experimental	mAb	CD3E
sar443216	Agonist	experimental	mAb	CD3E
shr1	Agonist	experimental	mAb	CD3E
TNB-486	Agonist	experimental	mAb	CD3E
TNB-585	Agonist	experimental	mAb	CD3E
tqb2825	Agonist	experimental	mAb	CD3E agonist
tqb2934	Agonist	experimental	mAb	CD3E agonist
XMab-15426	Agonist	experimental	mAb	CD3E
xmab13676	Agonist	experimental	mAb	CD3E
xmab18968	Agonist	experimental	mAb	CD3E
xmab819	Agonist	experimental	mAb	cd3e
y150	Agonist	experimental	mAb	CD3E
otelixizumab	Binding agent	experimental	mAb	CD3E binding agent
resimmune	Binding agent	experimental	mAb	T-cell surface glycoprotein CD3 epsilon chain binding agent
teclistamab (Tecvayli)	Chelating agent	approved	mAb	CD3E chelating agent
catumaxomab (Removab)	Cross-linking agent	experimental	mAb	CD3E cross-linking agent
ertumaxomab	Cross-linking agent	experimental	mAb	T-cell surface glycoprotein CD3 epsilon chain cross-linking agent
medi-565	Cross-linking agent	experimental	mAb	CD3E cross-linking agent
amg 160	Immunity, passive	experimental	mAb	CD3E immunity, passive
amg 171	Immunity, passive	experimental	mAb	CD3E immunity, passive
amg 199	Immunity, passive	experimental	mAb	CD3E immunity, passive
amg 420	Immunity, passive	experimental	mAb	CD3E immunity, passive
amg 424	Immunity, passive	experimental	mAb	CD3E immunity, passive
amg 427	Immunity, passive	experimental	mAb	CD3E immunity, passive
amg 509	Immunity, passive	experimental	mAb	CD3E immunity, passive
amg 562	Immunity, passive	experimental	mAb	CD3E immunity, passive
amg 673	Immunity, passive	experimental	mAb	CD3E immunity, passive
amg 701	Immunity, passive	experimental	mAb	CD3E immunity, passive
amg 910	Immunity, passive	experimental	mAb	CD3E immunity, passive
amv564	Immunity, passive	experimental	mAb	CD3E immunity, passive
anti-cd3 conjugated to recombinant ricin a chain	Immunity, passive	experimental	mAb	CD3E immunity, passive
anti-cd3-muc1 bispecific antibody	Immunity, passive	experimental	mAb	CD3E immunity, passive
bi 764532	Immunity, passive	experimental	mAb	CD3E immunity, passive
btrc4017a	Immunity, passive	experimental	mAb	CD3E immunity, passive
cc-93269	Immunity, passive	experimental	mAb	CD3E immunity, passive
cc-95266	Immunity, passive	experimental	mAb	CD3E immunity, passive
cc-99712	Immunity, passive	experimental	mAb	CD3E immunity, passive
cd20-tcb	Immunity, passive	experimental	mAb	CD3E immunity, passive
cibisatamab	Immunity, passive	experimental	mAb	CD3E immunity, passive
foralumab	Immunity, passive	experimental	mAb	CD3E immunity, passive
gbr 1342	Immunity, passive	experimental	mAb	CD3E immunity, passive
gem333	Immunity, passive	experimental	mAb	CD3E immunity, passive
gem3psca	Immunity, passive	experimental	mAb	CD3E immunity, passive
gen1044	Immunity, passive	experimental	mAb	CD3E immunity, passive
gnr-084	Immunity, passive	experimental	mAb	CD3E immunity, passive
hpn328	Immunity, passive	experimental	mAb	CD3E immunity, passive
hpn424	Immunity, passive	experimental	mAb	CD3E immunity, passive
hpn536	Immunity, passive	experimental	mAb	CD3E immunity, passive
igm-2323	Immunity, passive	experimental	mAb	CD3E immunity, passive
imc-c103c	Immunity, passive	experimental	mAb	CD3E immunity, passive
jnj-63898081	Immunity, passive	experimental	mAb	CD3E immunity, passive
jnj-67571244	Immunity, passive	experimental	mAb	CD3E immunity, passive
linvoseltamab (Lynozyfic)	Immunity, passive	approved	mAb	CD3E immunity, passive
m701	Immunity, passive	experimental	mAb	CD3E immunity, passive
m802	Immunity, passive	experimental	mAb	CD3E immunity, passive
ono-4685	Immunity, passive	experimental	mAb	CD3E immunity, passive
otelixizumab	Immunity, passive	experimental	mAb	CD3E immunity, passive
pf-06671008	Immunity, passive	experimental	mAb	CD3E immunity, passive
pf-07062119	Immunity, passive	experimental	mAb	CD3E immunity, passive
psmaxcd3	Immunity, passive	experimental	mAb	CD3E immunity, passive
regn1979	Immunity, passive	experimental	mAb	CD3E immunity, passive
regn4018	Immunity, passive	experimental	mAb	CD3E immunity, passive
regn5459	Immunity, passive	experimental	mAb	CD3E immunity, passive
ro6895882	Immunity, passive	experimental	mAb	CD3E immunity, passive
ro7293583	Immunity, passive	experimental	mAb	CD3E immunity, passive
sar440234	Immunity, passive	experimental	mAb	CD3E immunity, passive
sl-172154	Immunity, passive	experimental	mAb	CD3E immunity, passive
tarlatamab (IMDELLTRA)	Immunity, passive	approved	mAb	CD3E immunity, passive
teplizumab (Tzield)	Immunity, passive	approved	mAb	CD3E immunity, passive
tnb-383b	Immunity, passive	experimental	mAb	CD3E immunity, passive
visilizumab	Immunity, passive	experimental	mAb	CD3E immunity, passive
xmab13676	Immunity, passive	experimental	mAb	CD3E immunity, passive
xmab14045	Immunity, passive	experimental	mAb	CD3E immunity, passive
xmab18087	Immunity, passive	experimental	mAb	CD3E immunity, passive
A-319	Inhibitor	experimental	mAb	CD3E inhibitor
amx 818	Inhibitor	experimental	Recombinant protein	CD3E inhibitor
apvo436	Inhibitor	experimental	mAb	CD3E inhibitor
bfcr4350a	Inhibitor	experimental	mAb	CD3E inhibitor
isb 1302	Inhibitor	experimental	mAb	CD3E inhibitor
mgd014	Inhibitor	experimental	mAb	CD3E inhibitor
muromonab cd3 (Orthoclone OKT3)	Inhibitor	approved	mAb	CD3E inhibitor
regn7041	Inhibitor	experimental	mAb	CD3E inhibitor
visilizumab	Inhibitor	experimental	mAb	CD3E inhibitor
teplizumab (Tzield)	Other	approved	mAb	CD3E other