lotiglipron

Small moleculeexperimental

Clinical trial activity

11 trials · 1 clinical orgs · 0 marketing orgs

Phase 1
10
Phase 2
1
Phase 3
0
Phase 4
0

Earliest trial started Nov 5, 2019 (NCT04148209)

Timeline

2010s

  1. Jan 1, 2019

    Earliest Phase 1 Sponsor(trial)

2020s

  1. Jan 1, 2022

    Earliest Phase 2 Sponsor(trial)

Indications

Mechanism of action

Chemistry & pharmacology

Loading structure…

SMILES

C[C@]1(c2ccc(Cl)cn2)Oc2cccc(C3CCN(Cc4nc5ccc(C(=O)O)cc5n4C[C@@H]4CCO4)CC3)c2O1
Mol. weight
575.07 g/mol
Lipinski Ro5
2 violation(s)
Rule of 3
No
Chirality
Single Stereoisomer
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT05788328Phase 1Mar 27, 2023Pfizer
NCT05745701Phase 1Feb 22, 2023Pfizer
NCT05671653Phase 1Jan 19, 2023Pfizer
NCT05677867Phase 1Jan 18, 2023Pfizer
NCT05652647Phase 1Dec 15, 2022Pfizer
NCT05579977Phase 2Oct 27, 2022Pfizer
NCT05510245Phase 1Aug 29, 2022Pfizer
NCT05478603Phase 1Aug 1, 2022Pfizer
NCT05158244Phase 1Dec 15, 2021Pfizer
NCT04305587Phase 1Mar 16, 2020Pfizer
NCT04148209Phase 1Nov 5, 2019Pfizer
Showing 11 of 11 trials
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Organizations

Research & Development (1)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
PfizerFor profit111122019
1 organizations
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