antroquinonol
Small moleculeexperimental
Clinical trial activity
10 trials · 8 clinical orgs · 0 marketing orgs
Phase 1
2
Phase 2
9
Phase 3
0
Phase 4
0
Earliest trial started Dec 1, 2010 (NCT01134016)
Timeline
Indications
Mechanism of action
- Protein farnesyltransferaseINHIBITOR
Protein farnesyltransferase inhibitor
Chemistry & pharmacology
Loading structure…
SMILES
COC1=C(OC)[C@H](O)[C@H](C/C=C(\C)CC/C=C(\C)CCC=C(C)C)[C@@H](C)C1=O- Mol. weight
- 390.56 g/mol
- Lipinski Ro5
- 1 violation(s)
- Rule of 3
- No
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL3235620 ↗
Also known as
- antroquinonol
- antroquinonol
- antroquinonol
- antroquinonol
- antroquinonol d
- hocena
- hocena
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT04523181 | Phase 2 | Oct 8, 2020 | Golden Biotechnology Corp. |
| NCT03823352 | Phase 2 | Feb 20, 2019 | Golden Biotechnology Corp. |
| NCT04112147 | Phase 2 | Aug 10, 2018 | Chung Shan Medical University, Golden Biotechnology Corp. |
| NCT03625102 | Phase 2 | Aug 1, 2018 | Chung Shan Medical University, Golden Biotechnology Corp. |
| NCT04110873 | Phase 2 | Jul 27, 2018 | Chung Shan Medical University, Golden Biotechnology Corp. |
| NCT03622463 | Phase 2 | Jul 17, 2018 | Chung Shan Medical University, Golden Biotechnology Corp. |
| NCT03310632 | Phase 1/Phase 2 (Phase 2) | Dec 1, 2017 | Covance, Golden Biotechnology Corp. |
| NCT02719028 | Phase 2 | May 1, 2016 | Golden Biotechnology Corp., National Taiwan University |
| NCT02047344 | Phase 2 | Oct 1, 2013 | Golden Biotechnology Corp., ICON |
| NCT01134016 | Phase 1 | Dec 1, 2010 | Golden Biotechnology Corp., Government of Taiwan, PharmaNet, Taipei Veteran General hospital |
Showing 10 of 10 trials
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Organizations
Research & Development (8)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Golden Biotechnology Corp. | For profit | 10 | 8 | 2 | 2010 |
| Chung Shan Medical University | Academic/Hospital | 4 | 2 | 1 | 2018 |
| Covance | For profit | 1 | 0 | 1 | 2017 |
| Government of Taiwan | Government | 1 | 0 | 1 | 2010 |
| ICON | For profit | 1 | 0 | 1 | 2013 |
| National Taiwan University | Academic/Hospital | 1 | 0 | 1 | 2016 |
| PharmaNet | For profit | 1 | 0 | 1 | 2010 |
| Taipei Veteran General hospital | Government | 1 | 0 | 1 | 2010 |
8 organizations
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