CDEK
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fenebrutinib

Small moleculeexperimental

Clinical trial activity

7 trials · 2 clinical orgs · 0 marketing orgs

Phase 1
1
Phase 2
6
Phase 3
3
Phase 4
0

Earliest trial started Jul 27, 2018 (NCT03596632)

Timeline

2010s

  1. Jan 1, 2018

    Earliest Phase 1 Sponsor(trial)

  2. Jan 1, 2018

    Earliest Phase 2 Sponsor(trial)

2020s

  1. Jan 1, 2020

    Earliest Phase 3 Sponsor(trial)

Indications

Studied for

Mechanism of action

Chemistry & pharmacology

Loading structure…

SMILES

C[C@H]1CN(C2COC2)CCN1c1ccc(Nc2cc(-c3ccnc(N4CCn5c(cc6c5CC(C)(C)C6)C4=O)c3CO)cn(C)c2=O)nc1
Mol. weight
664.81 g/mol
Lipinski Ro5
2 violation(s)
Rule of 3
No
Chirality
Single Stereoisomer
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT07161258Phase 2Oct 6, 2025Roche
NCT05119569Phase 2Nov 29, 2021Roche
NCT04586023Phase 3Dec 26, 2020Roche
NCT04586010Phase 3Dec 18, 2020Roche
NCT04544449Phase 3Oct 26, 2020Roche
NCT03693625Phase 2Sep 27, 2018Genentech, Roche
NCT03596632Phase 1Jul 27, 2018Roche
Showing 7 of 7 trials
Page 1 / 1

Organizations

Research & Development (2)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
RocheFor profit7632018
GenentechFor profit1112018
2 organizations
Page 1 / 1