favipiravir

Small moleculeexperimentalCOVID-19

Favipiravir, sold under the brand name Avigan among others, is an antiviral medication used to treat influenza in Japan. It is also being studied to treat a number of other viral infections, including SARS-CoV-2. Like the experimental antiviral drugs T-1105 and T-1106, it is a pyrazinecarboxamide derivative. — Wikipedia

Clinical trial activity

83 trials · 196 clinical orgs · 0 marketing orgs

Phase 1
18
Phase 2
51
Phase 3
36
Phase 4
3

Earliest trial started Feb 1, 2010 (NCT01068912)

Timeline

2010s

  1. Jan 1, 2010

    Earliest Phase 2 Sponsor(trial)

  2. Jan 1, 2011

    Earliest Phase 1 Sponsor(trial)

  3. Jan 1, 2013

    Earliest Phase 3 Sponsor(trial)

Indications

Approved for

Mechanism of action

Chemistry & pharmacology

Loading structure…

SMILES

NC(=O)c1nc(F)cnc1O
Mol. weight
157.1 g/mol
Lipinski Ro5
Pass
Rule of 3
No
Chirality
Achiral Molecule
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Prodrug

Sources

Also known as

  • 6-fluoro-3-hydroxy-2-pyrazinecarboxamide
  • avigan
  • favipiravir
  • favipiravir
  • favipiravir
  • favipiravir
  • favipiravir
  • favipiravir
  • favipiravir
  • favipiravir
  • t-705
  • t-705
  • t-705
  • t-705 cpd

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT06860334Phase 2Jul 1, 2025University of Liverpool
NCT06574503Phase 3Sep 30, 2024Qingfeng Pharmaceutical Group
NCT06643156Phase 1Sep 27, 2024Qingfeng Pharmaceutical Group
NCT06678542Phase 1Sep 27, 2024Qingfeng Pharmaceutical Group
NCT06573008Phase 3Aug 31, 2024Qingfeng Pharmaceutical Group
NCT06488300Phase 2Jul 1, 2024University of Oxford
NCT06212336Phase 2/Phase 3 (Phase 3)Jul 1, 2024Alex Ekwueme Federal University Teaching Hospital, Alliance for International Medical Action, Bernhard Nocht Institute for Tropical Medicine, Centre de Recherche Médicale de Lambaréné, Federal Medical Centre, Owo, Government of Cote d'Ivoire, Government of France, Irrua Specialist Teaching Hospital, Medecins Sans Frontieres, University of Bordeaux, University of Hamburg, University of North Carolina at Chapel Hill
NCT06024421Phase 1Nov 30, 2023Institut National de la Santé Et de la Recherche Médicale, France, Toyama, University of Bordeaux
NCT05940545Phase 1/Phase 2 (Phase 2)Jul 12, 2023University of Liverpool
NCT05814926Phase 1Apr 26, 2023Capital Medical University, Qingfeng Pharmaceutical Group
NCT05789342Phase 1Feb 15, 2023Peking University, Qingfeng Pharmaceutical Group
NCT05648448Phase 2Dec 22, 2022University of Oxford
NCT05474755Phase 3Jul 28, 2022Peking University, Qingfeng Pharmaceutical Group
NCT05279235Phase 3Mar 8, 2022Government of China, Shanghai Junshi Bioscience Co.,Ltd., Sponsor GmbH
NCT05218616Phase 1Jan 21, 2022Government of Belarus, JLLC NatiVita
NCT05103241Phase 1Nov 30, 2021Qingfeng Pharmaceutical Group
NCT05502081Phase 4Nov 1, 2021Tanta University
NCT04918927Phase 2Oct 12, 2021Government of Mexico, Hakken Enterprise, Instituto Mexicano del Seguro Social, National Polytechnic Institute, Mexico, Siegfried, Strides Pharma Science, Universidad Autonoma De Guadalajara, Mexico, University of London
NCT05041907Phase 2Sep 30, 2021University of Oxford
NCT05185284Phase 3Aug 11, 2021Moscow State Clinical Hospital №50, Promomed, LLC
Showing 20 of 83 trials
Page 1 / 5

Organizations

Research & Development (196)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
Qingfeng Pharmaceutical GroupFor profit101032020
Peking UniversityAcademic/Hospital6242018
Farmagen Ar-Ge Biyot. Ltd. StiFor profit5112020
MediVieFor profit5532010
Novagenix Bioanalytical Drug R&D CenterFor profit5012020
Institut National de la Santé Et de la Recherche Médicale, FranceAcademic/Hospital4322014
University of BordeauxAcademic/Hospital4132020
University of OxfordAcademic/Hospital4312018
Capital Medical UniversityAcademic/Hospital3232018
Tanta UniversityAcademic/Hospital3222020
University of LondonAcademic/Hospital3222020
Alliance for International Medical ActionAcademic/Hospital2022021
Ankara Yildirim Beyazıt UniversityAcademic/Hospital2012020
Appili Therapeutics Inc.For profit2222020
Beijing Institute of Pharmacology and ToxicologyAcademic/Hospital2112014
Bernhard Nocht Institute for Tropical MedicineAcademic/Hospital2122021
Centers for Disease Control and Prevention, ChinaGovernment2012014
Federal Medical Centre, OwoAcademic/Hospital2022021
Government of HungaryGovernment2022020
Government of MexicoGovernment2112021
196 organizations
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