cilofexor

Small moleculeexperimental

Clinical trial activity

12 trials · 3 clinical orgs · 0 marketing orgs

Phase 1
3
Phase 2
9
Phase 3
1
Phase 4
0

Earliest trial started Jan 1, 2016 (NCT02654002)

Timeline

2010s

  1. Jan 1, 2016

    Earliest Phase 1 Sponsor(trial)

  2. Jan 1, 2016

    Earliest Phase 2 Sponsor(trial)

  3. Jan 1, 2019

    Earliest Phase 3 Sponsor(trial)

Indications

Mechanism of action

Chemistry & pharmacology

Loading structure…

SMILES

O=C(O)c1ccnc(N2CC(O)(c3ccc(OCc4c(-c5c(Cl)cccc5Cl)noc4C4CC4)cc3Cl)C2)c1
Mol. weight
586.86 g/mol
Lipinski Ro5
2 violation(s)
Rule of 3
No
Chirality
Achiral Molecule
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • gs-9674

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT04971785Phase 2Aug 9, 2021Gilead Sciences, Novo Nordisk
NCT04702490Phase 2Dec 15, 2020Metacrine, Inc.
NCT04060147Phase 1Aug 31, 2019Gilead Sciences
NCT03987074Phase 2Aug 31, 2019Gilead Sciences, Novo Nordisk
NCT03890120Phase 3Mar 27, 2019Gilead Sciences
NCT03449446Phase 2Mar 21, 2018Gilead Sciences
NCT02943447Phase 2Dec 1, 2016Gilead Sciences
NCT02943460Phase 2Nov 29, 2016Gilead Sciences
NCT02854605Phase 2Oct 26, 2016Gilead Sciences
NCT02808312Phase 1Jul 13, 2016Gilead Sciences
NCT02781584Phase 2Jul 13, 2016Gilead Sciences
NCT02654002Phase 1Jan 1, 2016Gilead Sciences
Showing 12 of 12 trials
Page 1 / 1

Organizations

Research & Development (3)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
Gilead SciencesFor profit111132016
Novo NordiskFor profit2012019
Metacrine, Inc.For profit1112020
3 organizations
Page 1 / 1