131 i-omburtamab
mAbexperimentalADC
Clinical trial activity
9 trials · 8 clinical orgs · 0 marketing orgs
Phase 1
4
Phase 2
2
Phase 3
1
Phase 4
0
Earliest trial started Oct 1, 2001 (NCT00582608)
Timeline
Indications
Mechanism of action
- CD276 antigenINHIBITOR
CD276 inhibitor
Chemistry & pharmacology
- Inorganic
- No
- Polymer
- No
- Multi-specific
- No
- Payload
- 131-iodine
Oral
No
Parenteral
No
Topical
No
Sources
- NCATSB6PMV8U3C4 ↗
- ChEMBLCHEMBL2109682 ↗
Also known as
- 131i-8h9
- 8h9
- 8h9
- 8h9 (131i)
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT05063357 | Phase 1 | Dec 31, 2021 | Invicro, LabCorp, Y-Mabs, Inc |
| NCT04743661 | Phase 2 | Oct 1, 2021 | Memorial Sloan-Kettering Cancer Center, National Cancer Institute (NCI), Pediatric Brain Tumor Consortium, Y-Mabs, Inc |
| NCT04022213 | Phase 2 | Jul 15, 2019 | Memorial Sloan-Kettering Cancer Center, Y-Mabs, Inc |
| NCT03275402 | Phase 2/Phase 3 (Phase 3) | Sep 30, 2018 | Y-Mabs, Inc |
| NCT01502917 | Phase 1 | Dec 31, 2011 | Memorial Sloan-Kettering Cancer Center, Y-Mabs, Inc |
| NCT01099644 | Phase 1 | Apr 1, 2010 | Cornell University |
| NCT00089245 | Phase 1 | Jul 1, 2004 | Cornell University, National Cancer Institute (NCI), New York University |
| NCT00582608 | N/A | Oct 1, 2001 | Cornell University |
| NCT05064306 | N/A | — | Memorial Sloan-Kettering Cancer Center, Y-Mabs, Inc |
Showing 9 of 9 trials
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Organizations
Research & Development (8)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Y-Mabs, Inc | For profit | 6 | 3 | 4 | 2011 |
| Memorial Sloan-Kettering Cancer Center | Academic/Hospital | 4 | 2 | 3 | 2011 |
| Cornell University | Academic/Hospital | 3 | 3 | 2 | 2001 |
| National Cancer Institute (NCI) | Government | 2 | 0 | 2 | 2004 |
| Invicro | For profit | 1 | 0 | 1 | 2021 |
| LabCorp | For profit | 1 | 0 | 1 | 2021 |
| New York University | Academic/Hospital | 1 | 0 | 1 | 2004 |
| Pediatric Brain Tumor Consortium | Academic/Hospital | 1 | 1 | 1 | 2021 |
8 organizations
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