lipase

Biologicalapproved

Approved

Dec 9, 1996

Lipase is a class of enzymes that catalyzes the hydrolysis of fats. Some lipases display broad substrate scope including esters of cholesterol, phospholipids, and of lipid-soluble vitamins and sphingomyelinases; however, these are usually treated separately from "conventional" lipases. Unlike esterases, which function in water, lipases "are activated only when adsorbed to an oil–water interface". Lipases perform essential roles in digestion, transport and processing of dietary lipids in most, if not all, organisms. — Wikipedia

Clinical trial activity

0 trials · 0 clinical orgs · 7 marketing orgs

Phase 1
0
Phase 2
0
Phase 3
0
Phase 4
0

Timeline

1990s

  1. Dec 9, 1996

    Organon — Earliest FDA Approval

  2. Dec 9, 1996

    Organon — NDA Secondary Org

  3. Dec 9, 1996

    Organon — NDA Organization

2000s

  1. Apr 30, 2009

    AbbVie — NDA Secondary Org

  2. Aug 27, 2009

    Forest Laboratories — NDA Secondary Org

  3. Aug 27, 2009

    Eurand Pharmaceuticals — Marketing Organization

  4. Aug 27, 2009

    Eurand Pharmaceuticals — NDA Secondary Org

2010s

  1. Apr 12, 2010

    Vivus — NDA Secondary Org

  2. Mar 1, 2012

    Allergan PLC (2015) — Marketing Organization

  3. Mar 1, 2012

    Allergan PLC (2015) — NDA Secondary Org

  4. May 17, 2012

    Digestive Care, Inc. — NDA Secondary Org

Indications

Mechanism of action

Combination products

Approval history

  • approvedDec 9, 1996

Chemistry & pharmacology

Oral

No

Parenteral

No

Topical

No

Sources

Organizations

Marketing (11)

OrganizationOrg typeRelationshipDate
AbbVieFor profitNDA2Apr 30, 2009
Allergan PLC (2015)For profitMKTGMar 1, 2012
Allergan PLC (2015)For profitNDA2Mar 1, 2012
Digestive Care, Inc.For profitNDA2May 17, 2012
Eurand PharmaceuticalsFor profitMKTGAug 27, 2009
Eurand PharmaceuticalsFor profitNDA2Aug 27, 2009
Eurand PharmaceuticalsFor profitMKTGAug 27, 2009
Forest LaboratoriesFor profitNDA2Aug 27, 2009
OrganonFor profitNDA2Dec 9, 1996
OrganonFor profitNDADec 9, 1996
VivusFor profitNDA2Apr 12, 2010