lipase
Approved
Dec 9, 1996
Lipase is a class of enzymes that catalyzes the hydrolysis of fats. Some lipases display broad substrate scope including esters of cholesterol, phospholipids, and of lipid-soluble vitamins and sphingomyelinases; however, these are usually treated separately from "conventional" lipases. Unlike esterases, which function in water, lipases "are activated only when adsorbed to an oil–water interface". Lipases perform essential roles in digestion, transport and processing of dietary lipids in most, if not all, organisms. — Wikipedia
Clinical trial activity
0 trials · 0 clinical orgs · 7 marketing orgs
Timeline
1990s
2000s
- Apr 30, 2009
AbbVie — NDA Secondary Org
- Aug 27, 2009
Forest Laboratories — NDA Secondary Org
- Aug 27, 2009
Eurand Pharmaceuticals — Marketing Organization
- Aug 27, 2009
Eurand Pharmaceuticals — NDA Secondary Org
2010s
- Apr 12, 2010
Vivus — NDA Secondary Org
- Mar 1, 2012
Allergan PLC (2015) — Marketing Organization
- Mar 1, 2012
Allergan PLC (2015) — NDA Secondary Org
- May 17, 2012
Digestive Care, Inc. — NDA Secondary Org
Indications
Approved for
Mechanism of action
- excipientOTHER
excipient other
Combination products
pancrelipase
with pancrelipase, amylase
Approval history
- approvedDec 9, 1996
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaLipase ↗
Organizations
Marketing (11)
| Organization | Org type | Relationship | Date |
|---|---|---|---|
| AbbVie | For profit | NDA2 | Apr 30, 2009 |
| Allergan PLC (2015) | For profit | MKTG | Mar 1, 2012 |
| Allergan PLC (2015) | For profit | NDA2 | Mar 1, 2012 |
| Digestive Care, Inc. | For profit | NDA2 | May 17, 2012 |
| Eurand Pharmaceuticals | For profit | MKTG | Aug 27, 2009 |
| Eurand Pharmaceuticals | For profit | NDA2 | Aug 27, 2009 |
| Eurand Pharmaceuticals | For profit | MKTG | Aug 27, 2009 |
| Forest Laboratories | For profit | NDA2 | Aug 27, 2009 |
| Organon | For profit | NDA2 | Dec 9, 1996 |
| Organon | For profit | NDA | Dec 9, 1996 |
| Vivus | For profit | NDA2 | Apr 12, 2010 |