amylase
Approved
Dec 9, 1996
An amylase is an enzyme that catalyses the hydrolysis of starch into sugars. Amylase is present in the saliva of humans and some other mammals, where it begins the chemical process of digestion. Foods that contain large amounts of starch but little sugar, such as rice and potatoes, may acquire a slightly sweet taste as they are chewed because amylase degrades some of their starch into sugar. The pancreas and salivary gland make amylase to hydrolyse dietary starch into disaccharides and trisaccharides which are converted by other enzymes to glucose to supply the body with energy. Plants and some bacteria also produce amylase. Specific amylase proteins are designated by different Greek letters. All amylases are glycoside hydrolases and act on α-1,4-glycosidic bonds. — Wikipedia
Clinical trial activity
1 trials · 1 clinical orgs · 7 marketing orgs
Earliest trial started Sep 30, 2010 (NCT01267565)
Timeline
2000s
- Apr 30, 2009
AbbVie — NDA Secondary Org
- Aug 27, 2009
Eurand Pharmaceuticals — Marketing Organization
- Aug 27, 2009
Forest Laboratories — NDA Secondary Org
- Aug 27, 2009
Eurand Pharmaceuticals — NDA Secondary Org
2010s
- Apr 12, 2010
Vivus — NDA Secondary Org
- Mar 1, 2012
Allergan PLC (2015) — Marketing Organization
- Mar 1, 2012
Allergan PLC (2015) — NDA Secondary Org
- May 17, 2012
Digestive Care, Inc. — NDA Secondary Org
Indications
Approved for
Mechanism of action
- excipientOTHER
excipient other
Combination products
pancrelipase
with pancrelipase, lipase
Approval history
- approvedDec 9, 1996
Chemistry & pharmacology
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
- Delivery
- Oral
- Availability
- Prescription Only
Oral
Yes
Parenteral
No
Topical
No
Sources
- WikipediaAmylase ↗
- ChEMBLCHEMBL1201648 ↗
Also known as
- amylase
- amylase
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT01267565 | N/A | Sep 30, 2010 | University of Bordeaux |
Organizations
Research & Development (1)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| University of Bordeaux | Academic/Hospital | 1 | 1 | 1 | 2010 |
Marketing (10)
| Organization | Org type | Relationship | Date |
|---|---|---|---|
| AbbVie | For profit | NDA2 | Apr 30, 2009 |
| Allergan PLC (2015) | For profit | MKTG | Mar 1, 2012 |
| Allergan PLC (2015) | For profit | NDA2 | Mar 1, 2012 |
| Digestive Care, Inc. | For profit | NDA2 | May 17, 2012 |
| Eurand Pharmaceuticals | For profit | MKTG | Aug 27, 2009 |
| Eurand Pharmaceuticals | For profit | NDA2 | Aug 27, 2009 |
| Eurand Pharmaceuticals | For profit | MKTG | Aug 27, 2009 |
| Forest Laboratories | For profit | NDA2 | Aug 27, 2009 |
| Organon | For profit | NDA | Dec 9, 1996 |
| Vivus | For profit | NDA2 | Apr 12, 2010 |