thonzonium bromide
Small moleculeapproved
Approved
May 17, 1962
Thonzonium bromide is a monocationic detergent. A solution of it is thus a surfactant and a detergent that promotes tissue contact by dispersion and penetration of the cellular debris and exudate of the containing solution. — Wikipedia
Clinical trial activity
0 trials · 0 clinical orgs · 2 marketing orgs
Phase 1
0
Phase 2
0
Phase 3
0
Phase 4
0
Timeline
1960s
- May 17, 1962
Endo Pharmaceuticals — Earliest FDA Approval
- May 17, 1962
Endo Pharmaceuticals — NDA Secondary Org
- May 17, 1962
Endo Pharmaceuticals — NDA Organization
- May 17, 1962
PH HEALTH — NDA Secondary Org
Indications
Approved for
Mechanism of action
- Neurokinin 1 receptorINHIBITOR
TACR1 inhibitor
Combination products
Approval history
- approvedMay 17, 1962
Chemistry & pharmacology
Loading structure…
SMILES
CCCCCCCCCCCCCCCC[N+](C)(C)CCN(Cc1ccc(OC)cc1)c1ncccn1.[Br-]- Mol. weight
- 591.72 g/mol
- Lipinski Ro5
- 2 violation(s)
- Rule of 3
- No
- Chirality
- Achiral Molecule
- Inorganic
- No
- Polymer
- No
- Delivery
- Topical
- Availability
- Prescription Only
Oral
No
Parenteral
No
Topical
Yes
Sources
- WikipediaThonzonium bromide ↗
- ChEMBLCHEMBL1200883 ↗
Also known as
- nc-1264
- nc-1264
- thonzide
- thonzide
- thonzide
- thonzonium bromide
- thonzonium bromide
- thonzonium bromide
- thonzonium bromide
- tonzonium bromide
- tonzonium bromide
- tonzonium bromide
Organizations
Marketing (4)
| Organization | Org type | Relationship | Date |
|---|---|---|---|
| Endo Pharmaceuticals | For profit | NDA2 | May 17, 1962 |
| Endo Pharmaceuticals | For profit | SYN | May 17, 1962 |
| Endo Pharmaceuticals | For profit | NDA | May 17, 1962 |
| PH HEALTH | For profit | NDA2 | May 17, 1962 |