psyllium
Botanicalexperimental
Psyllium, or Isabgol or ispaghula, is the common name used for several members of the plant genus Plantago whose seeds are used commercially for the production of mucilage. Psyllium is mainly used as a dietary fiber to relieve symptoms of both constipation and mild diarrhea, and occasionally as a food thickener. Allergy to psyllium is common in workers frequently exposed to the substance. — Wikipedia
Clinical trial activity
50 trials · 58 clinical orgs · 0 marketing orgs
Phase 1
1
Phase 2
7
Phase 3
4
Phase 4
6
Earliest trial started May 1, 1988 (NCT01582282)
Timeline
Indications
Approved for
Studied for
- Colitis, Ulcerative · Phase 2
- Constipation · Phase 4
- Diabetes Mellitus, Type 2 · Phase 4
- Dyslipidemias · Phase 4
- Fecal Incontinence · Phase 2/Phase 3
- Fissure in Ano · Phase 2/Phase 3
- Flushing · Phase 4
- Gastroesophageal Reflux · Phase 4
- Healthy Volunteers · Phase 2
- Hypercholesterolemia · Phase 4
- Hyperlipidemias · Phase 4
- Inflammatory Bowel Diseases · Phase 2
- Irritable Bowel Syndrome · Phase 3
- Obesity · Phase 2
- Urinary Incontinence · Phase 4
Mechanism of action
- Unspecified targetSupplementation
supplementation
Chemistry & pharmacology
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaPsyllium ↗
- NCATS0SHO53407G ↗
- ChEMBLCHEMBL2108126 ↗
- NCATSY2HNG56689 ↗
Also known as
- hydrocil instant
- metamucil
- metamucil
- modane bulk
- mylanta fiber
- plantago
- plantago
- plantago seed
- plantago seed
- plantain
- psyllium
- psyllium
- psyllium
- psyllium
- psyllium husk
- psyllium husk
- psyllium husk
- syllact
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT07202481 | N/A | Oct 31, 2025 | Federal University of Minas Gerais |
| NCT06785831 | N/A | Jan 20, 2025 | Nutrition Institute, Slovenia, University of Ljubljana |
| NCT06639984 | Phase 3 | Nov 1, 2024 | Duke University, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) |
| NCT06551948 | N/A | Jan 1, 2024 | University of East Anglia, University of Nottingham |
| NCT06972134 | N/A | Dec 15, 2023 | Duhok University |
| NCT06166615 | Phase 2/Phase 3 (Phase 3) | Dec 15, 2023 | Seoul National University |
| NCT06291272 | N/A | Oct 15, 2023 | Quadram Institute, University of Nottingham |
| NCT05906589 | N/A | Jul 25, 2023 | University of Aberdeen |
| NCT05911347 | N/A | May 9, 2023 | University of East Anglia, University of Nottingham |
| NCT05528146 | N/A | Dec 1, 2022 | Hung Kaung University |
| NCT05619341 | N/A | Oct 28, 2022 | University of Nottingham |
| NCT05341180 | Phase 2/Phase 3 (Phase 3) | May 27, 2022 | All India Institute of Medical Sciences |
| NCT05825963 | N/A | Apr 12, 2022 | Okan University |
| NCT04806386 | N/A | Jul 21, 2021 | Harvard University |
| NCT04829760 | N/A | May 13, 2021 | University of Florida |
| NCT04695340 | N/A | Feb 1, 2021 | University of Nice Sophia Antipolis |
| NCT04619095 | N/A | Jan 1, 2021 | Alberta Children's Hospital Research Institute, University of Calgary |
| NCT04547790 | N/A | Dec 31, 2020 | Mayo Clinic |
| NCT06188728 | N/A | Sep 7, 2020 | University of Peshawar |
| NCT03998488 | Phase 2 | Jul 31, 2019 | Cornell University, Crohn's and Colitis Foundation |
Showing 20 of 50 trials
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Organizations
Research & Development (58)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| University of Nottingham | Academic/Hospital | 8 | 8 | 1 | 2013 |
| Procter and Gamble | For profit | 4 | 4 | 2 | 1988 |
| Department of Veteran Affairs | Government | 3 | 2 | 2 | 2008 |
| Duke University | Academic/Hospital | 2 | 1 | 2 | 2012 |
| Ironwood Pharmaceuticals | For profit | 2 | 0 | 1 | 2013 |
| Rush University | Academic/Hospital | 2 | 1 | 1 | 2010 |
| University of East Anglia | Academic/Hospital | 2 | 0 | 1 | 2023 |
| Aalborg University | Academic/Hospital | 1 | 1 | 1 | 2011 |
| Alberta Children's Hospital Research Institute | Academic/Hospital | 1 | 0 | 1 | 2021 |
| All India Institute of Medical Sciences | Academic/Hospital | 1 | 1 | 1 | 2022 |
| Canadian Cystic Fibrosis Foundation | Academic/Hospital | 1 | 0 | 1 | 2016 |
| Chinese University of Hong Kong | Academic/Hospital | 1 | 1 | 1 | 2009 |
| Cornell University | Academic/Hospital | 1 | 1 | 1 | 2019 |
| Crohn's and Colitis Foundation | Academic/Hospital | 1 | 0 | 1 | 2019 |
| Dr. Falk Pharma GmbH | For profit | 1 | 0 | 1 | 2012 |
| Duhok University | Academic/Hospital | 1 | 1 | 1 | 2023 |
| Federal University of Minas Gerais | Academic/Hospital | 1 | 1 | 1 | 2025 |
| Free University of Amsterdam | Academic/Hospital | 1 | 0 | 1 | 2016 |
| Harvard University | Academic/Hospital | 1 | 1 | 1 | 2021 |
| Hung Kaung University | Academic/Hospital | 1 | 1 | 1 | 2022 |
58 organizations
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