rapidosept

Clinical trial activity

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Mechanism of action

• Sodium channel alpha subunitBLOCKER

  Sodium channel alpha subunit blocker

  Dichlorobenzyl alcohol is a mild antiseptic, able to kill bacteria and viruses associated with mouth and throat infections. It is a common ingredient in throat lozenges such as Strepsils, Lorsept, and Gorpils. A low-pH throat lozenge containing dichlorobenzyl alcohol (1.2 mg) and amylmetacresol (0.6 mg) has been found to deactivate respiratory syncytial virus and SARS-Cov, but not adenovirus or rhinovirus. Dichlorobenzyl alcohol acts as a local anaesthetic and blocks voltage-gated Na channels in a local anaesthetic-like manner.

  • Sodium channel protein type 1 subunit alpha (SCN1A) ↗
  • Sodium channel protein type 5 subunit alpha (SCN5A) ↗
  • Sodium channel protein type 4 subunit alpha (SCN4A) ↗
  • Sodium channel protein type 7 subunit alpha (SCN7A) ↗
  • Sodium channel protein type 2 subunit alpha (SCN2A) ↗
  • Sodium channel protein type 9 subunit alpha (SCN9A) ↗
  • Sodium channel protein type 3 subunit alpha (SCN3A) ↗
  • Sodium channel protein type 11 subunit alpha (SCN11A) ↗
  • Sodium channel protein type 8 subunit alpha (SCN8A) ↗
  • Sodium channel protein type 10 subunit alpha (SCN10A) ↗
  • Sodium channel protein type I alpha subunit
  • Sodium channel protein type V alpha subunit
  • Sodium channel protein type IV alpha subunit
  • Sodium channel protein type VII alpha subunit
  • Sodium channel protein type IX alpha subunit
  • Sodium channel protein type II alpha subunit
  • Sodium channel protein type III alpha subunit
  • Sodium channel protein type XI alpha subunit
  • Sodium channel protein type VIII alpha subunit
  • Sodium channel protein type X alpha subunit
  • Sodium channel alpha subunits; brain (Types I, II, III)